Preparation of perfluorocarbon/fluoroalkyl polymer nanodroplets for cancer-targeted ultrasound contrast agents

Masamichi Nishihara, Kenji Imai, Masayuki Yokoyama

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10 Citations (Scopus)

Abstract

Perfluorocarbon (PFC) nanodroplets formed from PEG-bpoly(fluoroheptyl aspartate) were developed for a cancer-targeted ultrasound (US) contrast agent. 10% esterifed fluoroalkyl polymer (F10) was the optimal composition for PFC solubilization in aqueous solution. PFC/F10 nanodroplets showed echogenicity with US irradiation, and long-term stability of PFC nanodroplets at 4 °C was confirmed.

Original languageEnglish
Pages (from-to)556-557
Number of pages2
JournalChemistry Letters
Volume38
Issue number6
DOIs
Publication statusPublished - 2009
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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