Preparations of a RNA-lipid complex film and its physical properties.

Y. Hoshino, H. Nakayama, Y. Okahata

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

We extracted RNA (aver. 70-80 bases) from yeasts and prepared a RNA-lipid complex by replacing sodium counter cations with cationic amphiphiles (2C12N+2C1). The RNA-lipid complex was soluble only in organic solvents and formed a self-standing film by casting from organic solutions. The RNA film was physically strong, although its molecular weight is small and the RNA molecules are oriented in one direction by stretching the film, in which RNAs form intermolecular hydrogen bonds and show the physical strength of the film.

Original languageEnglish
Pages (from-to)61-62
Number of pages2
JournalNucleic acids research. Supplement (2001)
Issue number1
DOIs
Publication statusPublished - Jan 1 2001
Externally publishedYes

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