Preparations of a RNA-lipid complex film and its physical properties.

Y. Hoshino; H. Nakayama; Y. Okahata

doi:10.1093/nass/1.1.61

Preparations of a RNA-lipid complex film and its physical properties.

Y. Hoshino, H. Nakayama, Y. Okahata

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

We extracted RNA (aver. 70-80 bases) from yeasts and prepared a RNA-lipid complex by replacing sodium counter cations with cationic amphiphiles (2C12N+2C1). The RNA-lipid complex was soluble only in organic solvents and formed a self-standing film by casting from organic solutions. The RNA film was physically strong, although its molecular weight is small and the RNA molecules are oriented in one direction by stretching the film, in which RNAs form intermolecular hydrogen bonds and show the physical strength of the film.

Original language	English
Pages (from-to)	61-62
Number of pages	2
Journal	Nucleic acids research. Supplement (2001)
Issue number	1
DOIs	https://doi.org/10.1093/nass/1.1.61
Publication status	Published - 2001
Externally published	Yes

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1093/nass/1.1.61

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abstract = "We extracted RNA (aver. 70-80 bases) from yeasts and prepared a RNA-lipid complex by replacing sodium counter cations with cationic amphiphiles (2C12N+2C1). The RNA-lipid complex was soluble only in organic solvents and formed a self-standing film by casting from organic solutions. The RNA film was physically strong, although its molecular weight is small and the RNA molecules are oriented in one direction by stretching the film, in which RNAs form intermolecular hydrogen bonds and show the physical strength of the film.",

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AB - We extracted RNA (aver. 70-80 bases) from yeasts and prepared a RNA-lipid complex by replacing sodium counter cations with cationic amphiphiles (2C12N+2C1). The RNA-lipid complex was soluble only in organic solvents and formed a self-standing film by casting from organic solutions. The RNA film was physically strong, although its molecular weight is small and the RNA molecules are oriented in one direction by stretching the film, in which RNAs form intermolecular hydrogen bonds and show the physical strength of the film.

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Preparations of a RNA-lipid complex film and its physical properties.

Abstract

All Science Journal Classification (ASJC) codes

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