Presence of mitochondrial-DNA-like sequences in the human nuclear DNA

Teruhisa Tsuzuki, Hisayuki Nomiyama, Chiaki Setoyama, Shuichiro Maeda, Kazunori Shimada

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Two λ phage clones carrying contiguous human nuclear DNA sequences with extensive homology to non-contiguous human mitochondrial 16S ribosomal RNA sequences were isolated from a human gene library. The one clone carried mitochondrial-DNA(mtDNA)-like sequences flanked with two kinds of repetitive nuclear DNA sequences and the other carried mtDNA-like sequences, between unique nuclear DNA sequences and repetitive DNA sequences of Alu-family. These results demonstrate that mtDNA-like sequences are present in human nuclear DNA.

Original languageEnglish
Pages (from-to)223-229
Number of pages7
Issue number2-3
Publication statusPublished - Jan 1 1983


All Science Journal Classification (ASJC) codes

  • Genetics

Cite this

Tsuzuki, T., Nomiyama, H., Setoyama, C., Maeda, S., & Shimada, K. (1983). Presence of mitochondrial-DNA-like sequences in the human nuclear DNA. Gene, 25(2-3), 223-229.