Prevalence and characteristics of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries

Jin Yang Baek, In Ho Park, Thomas Man kit So, M. K. Lalitha, Nobuyuki Shimono, Rohani Md Yasin, Celia C. Carlos, Jennifer Perera, Visanu Thamlikitkul, Po Ren Hsueh, Pham Hung Van, Atef M. Shibl, Jae Hoon Song, Kwan Soo Ko

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The prevalence, antimicrobial susceptibility, and genotypes of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries were investigated. A total of 244 S. pneumoniae serogroup 6 isolates obtained from 11 Asian countries were included in this study. Of the 244 serogroup 6 isolates, 101 (41.4%) were typed as "putative serotype 6E," followed by serotypes 6A, 6B, 6C, and 6D (27.0, 20.1, 5.7, and 5.7%, respectively). Multilocus sequence typing revealed that clonal complex (CC) 90, including ST90 and its variants, was the most prevalent clonal group of "putative serotype 6E" isolates (n = 63; 62.4%). CC146 and CC315 were also found frequently in some of the countries. Most of the "putative serotype 6E" isolates showed very high resistance rates against cefuroxime, erythromycin, azithromycin, clarithromycin, clindamycin, and trimethoprim/sulfamethoxazole, probably due to their highly resistant to antimicrobials clone, CC90. Our results indicate that "putative serotype 6E" is prevalent in Asian countries. The clonal dissemination of "putative serotype 6E" isolates was also identified.

Original languageEnglish
Pages (from-to)334-337
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume80
Issue number4
DOIs
Publication statusPublished - Dec 1 2014

Fingerprint

Streptococcus pneumoniae
Serogroup
Multilocus Sequence Typing
Cefuroxime
Azithromycin
Clarithromycin
Clindamycin
Sulfamethoxazole Drug Combination Trimethoprim
Erythromycin
Clone Cells
Genotype

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

Cite this

Prevalence and characteristics of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries. / Baek, Jin Yang; Park, In Ho; So, Thomas Man kit; Lalitha, M. K.; Shimono, Nobuyuki; Yasin, Rohani Md; Carlos, Celia C.; Perera, Jennifer; Thamlikitkul, Visanu; Hsueh, Po Ren; Van, Pham Hung; Shibl, Atef M.; Song, Jae Hoon; Ko, Kwan Soo.

In: Diagnostic Microbiology and Infectious Disease, Vol. 80, No. 4, 01.12.2014, p. 334-337.

Research output: Contribution to journalArticle

Baek, JY, Park, IH, So, TMK, Lalitha, MK, Shimono, N, Yasin, RM, Carlos, CC, Perera, J, Thamlikitkul, V, Hsueh, PR, Van, PH, Shibl, AM, Song, JH & Ko, KS 2014, 'Prevalence and characteristics of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries', Diagnostic Microbiology and Infectious Disease, vol. 80, no. 4, pp. 334-337. https://doi.org/10.1016/j.diagmicrobio.2014.08.017
Baek, Jin Yang ; Park, In Ho ; So, Thomas Man kit ; Lalitha, M. K. ; Shimono, Nobuyuki ; Yasin, Rohani Md ; Carlos, Celia C. ; Perera, Jennifer ; Thamlikitkul, Visanu ; Hsueh, Po Ren ; Van, Pham Hung ; Shibl, Atef M. ; Song, Jae Hoon ; Ko, Kwan Soo. / Prevalence and characteristics of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries. In: Diagnostic Microbiology and Infectious Disease. 2014 ; Vol. 80, No. 4. pp. 334-337.
@article{26a8c54336334c08a3a1f62c1a37da13,
title = "Prevalence and characteristics of Streptococcus pneumoniae {"}putative serotype 6E{"} isolates from Asian countries",
abstract = "The prevalence, antimicrobial susceptibility, and genotypes of Streptococcus pneumoniae {"}putative serotype 6E{"} isolates from Asian countries were investigated. A total of 244 S. pneumoniae serogroup 6 isolates obtained from 11 Asian countries were included in this study. Of the 244 serogroup 6 isolates, 101 (41.4{\%}) were typed as {"}putative serotype 6E,{"} followed by serotypes 6A, 6B, 6C, and 6D (27.0, 20.1, 5.7, and 5.7{\%}, respectively). Multilocus sequence typing revealed that clonal complex (CC) 90, including ST90 and its variants, was the most prevalent clonal group of {"}putative serotype 6E{"} isolates (n = 63; 62.4{\%}). CC146 and CC315 were also found frequently in some of the countries. Most of the {"}putative serotype 6E{"} isolates showed very high resistance rates against cefuroxime, erythromycin, azithromycin, clarithromycin, clindamycin, and trimethoprim/sulfamethoxazole, probably due to their highly resistant to antimicrobials clone, CC90. Our results indicate that {"}putative serotype 6E{"} is prevalent in Asian countries. The clonal dissemination of {"}putative serotype 6E{"} isolates was also identified.",
author = "Baek, {Jin Yang} and Park, {In Ho} and So, {Thomas Man kit} and Lalitha, {M. K.} and Nobuyuki Shimono and Yasin, {Rohani Md} and Carlos, {Celia C.} and Jennifer Perera and Visanu Thamlikitkul and Hsueh, {Po Ren} and Van, {Pham Hung} and Shibl, {Atef M.} and Song, {Jae Hoon} and Ko, {Kwan Soo}",
year = "2014",
month = "12",
day = "1",
doi = "10.1016/j.diagmicrobio.2014.08.017",
language = "English",
volume = "80",
pages = "334--337",
journal = "Diagnostic Microbiology and Infectious Disease",
issn = "0732-8893",
publisher = "Elsevier Inc.",
number = "4",

}

TY - JOUR

T1 - Prevalence and characteristics of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries

AU - Baek, Jin Yang

AU - Park, In Ho

AU - So, Thomas Man kit

AU - Lalitha, M. K.

AU - Shimono, Nobuyuki

AU - Yasin, Rohani Md

AU - Carlos, Celia C.

AU - Perera, Jennifer

AU - Thamlikitkul, Visanu

AU - Hsueh, Po Ren

AU - Van, Pham Hung

AU - Shibl, Atef M.

AU - Song, Jae Hoon

AU - Ko, Kwan Soo

PY - 2014/12/1

Y1 - 2014/12/1

N2 - The prevalence, antimicrobial susceptibility, and genotypes of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries were investigated. A total of 244 S. pneumoniae serogroup 6 isolates obtained from 11 Asian countries were included in this study. Of the 244 serogroup 6 isolates, 101 (41.4%) were typed as "putative serotype 6E," followed by serotypes 6A, 6B, 6C, and 6D (27.0, 20.1, 5.7, and 5.7%, respectively). Multilocus sequence typing revealed that clonal complex (CC) 90, including ST90 and its variants, was the most prevalent clonal group of "putative serotype 6E" isolates (n = 63; 62.4%). CC146 and CC315 were also found frequently in some of the countries. Most of the "putative serotype 6E" isolates showed very high resistance rates against cefuroxime, erythromycin, azithromycin, clarithromycin, clindamycin, and trimethoprim/sulfamethoxazole, probably due to their highly resistant to antimicrobials clone, CC90. Our results indicate that "putative serotype 6E" is prevalent in Asian countries. The clonal dissemination of "putative serotype 6E" isolates was also identified.

AB - The prevalence, antimicrobial susceptibility, and genotypes of Streptococcus pneumoniae "putative serotype 6E" isolates from Asian countries were investigated. A total of 244 S. pneumoniae serogroup 6 isolates obtained from 11 Asian countries were included in this study. Of the 244 serogroup 6 isolates, 101 (41.4%) were typed as "putative serotype 6E," followed by serotypes 6A, 6B, 6C, and 6D (27.0, 20.1, 5.7, and 5.7%, respectively). Multilocus sequence typing revealed that clonal complex (CC) 90, including ST90 and its variants, was the most prevalent clonal group of "putative serotype 6E" isolates (n = 63; 62.4%). CC146 and CC315 were also found frequently in some of the countries. Most of the "putative serotype 6E" isolates showed very high resistance rates against cefuroxime, erythromycin, azithromycin, clarithromycin, clindamycin, and trimethoprim/sulfamethoxazole, probably due to their highly resistant to antimicrobials clone, CC90. Our results indicate that "putative serotype 6E" is prevalent in Asian countries. The clonal dissemination of "putative serotype 6E" isolates was also identified.

UR - http://www.scopus.com/inward/record.url?scp=84919355179&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84919355179&partnerID=8YFLogxK

U2 - 10.1016/j.diagmicrobio.2014.08.017

DO - 10.1016/j.diagmicrobio.2014.08.017

M3 - Article

C2 - 25439447

AN - SCOPUS:84919355179

VL - 80

SP - 334

EP - 337

JO - Diagnostic Microbiology and Infectious Disease

JF - Diagnostic Microbiology and Infectious Disease

SN - 0732-8893

IS - 4

ER -