Prevalence and risk factors for myopic retinopathy in a japanese population: The hisayama study

Tomoko Asakuma, Miho Yasuda, Toshiharu Ninomiya, Yoshihiro Noda, Satoshi Arakawa, Sawako Hashimoto, Kyoko Ohno-Matsui, Yutaka Kiyohara, Tatsuro Ishibashi

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Abstract

Purpose: To examine the prevalence of myopic retinopathy and its risk factors in a general Japanese population. Design: Population-based, cross-sectional study. Participants: In 2005, a total of 1969 Hisayama residents aged <40 years consented to participate in this study. Of these, 1892 subjects with adequate data were enrolled. Methods: Each participant underwent comprehensive physical and eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic retinopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, lacquer cracks, or macular atrophy. Main Outcome Measures: Prevalence of myopic retinopathy. Results: Thirty-three participants had myopic retinopathy and the prevalence was 1.7% (2.2% in women and 1.2% in men). The prevalence of myopic retinopathy increased significantly with advancing age. Diffuse chorioretinal atrophy, patchy chorioretinal atrophy, lacquer cracks, and macular atrophy were present in 1.7%, 0.4%, 0.2%, and 0.4% of subjects, respectively. In multivariate analysis, myopic retinopathy was significantly associated with older age (per 1 year: odds ratio [OR], 1.12; 95% confidence interval [CI], 1.07-1.18), female gender (OR, 3.29; 95% CI, 1.09-9.92), and longer axial length (per 1 mm: OR, 4.20; 95% CI, 3.03-5.83). Conclusions: The prevalence of myopic retinopathy was 1.7% in a general Japanese population. Older age, female gender, and longer axial length were significant risk factors for myopic retinopathy. Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article.

Original languageEnglish
Pages (from-to)1760-1765
Number of pages6
JournalOphthalmology
Volume119
Issue number9
DOIs
Publication statusPublished - Sep 1 2012

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Atrophy
Lacquer
Population
Odds Ratio
Confidence Intervals
Refractive Errors
Photography
Disclosure
Physical Examination
Multivariate Analysis
Color
Cross-Sectional Studies
Outcome Assessment (Health Care)

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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Prevalence and risk factors for myopic retinopathy in a japanese population : The hisayama study. / Asakuma, Tomoko; Yasuda, Miho; Ninomiya, Toshiharu; Noda, Yoshihiro; Arakawa, Satoshi; Hashimoto, Sawako; Ohno-Matsui, Kyoko; Kiyohara, Yutaka; Ishibashi, Tatsuro.

In: Ophthalmology, Vol. 119, No. 9, 01.09.2012, p. 1760-1765.

Research output: Contribution to journalArticle

Asakuma, T, Yasuda, M, Ninomiya, T, Noda, Y, Arakawa, S, Hashimoto, S, Ohno-Matsui, K, Kiyohara, Y & Ishibashi, T 2012, 'Prevalence and risk factors for myopic retinopathy in a japanese population: The hisayama study', Ophthalmology, vol. 119, no. 9, pp. 1760-1765. https://doi.org/10.1016/j.ophtha.2012.02.034
Asakuma, Tomoko ; Yasuda, Miho ; Ninomiya, Toshiharu ; Noda, Yoshihiro ; Arakawa, Satoshi ; Hashimoto, Sawako ; Ohno-Matsui, Kyoko ; Kiyohara, Yutaka ; Ishibashi, Tatsuro. / Prevalence and risk factors for myopic retinopathy in a japanese population : The hisayama study. In: Ophthalmology. 2012 ; Vol. 119, No. 9. pp. 1760-1765.
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abstract = "Purpose: To examine the prevalence of myopic retinopathy and its risk factors in a general Japanese population. Design: Population-based, cross-sectional study. Participants: In 2005, a total of 1969 Hisayama residents aged <40 years consented to participate in this study. Of these, 1892 subjects with adequate data were enrolled. Methods: Each participant underwent comprehensive physical and eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic retinopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, lacquer cracks, or macular atrophy. Main Outcome Measures: Prevalence of myopic retinopathy. Results: Thirty-three participants had myopic retinopathy and the prevalence was 1.7{\%} (2.2{\%} in women and 1.2{\%} in men). The prevalence of myopic retinopathy increased significantly with advancing age. Diffuse chorioretinal atrophy, patchy chorioretinal atrophy, lacquer cracks, and macular atrophy were present in 1.7{\%}, 0.4{\%}, 0.2{\%}, and 0.4{\%} of subjects, respectively. In multivariate analysis, myopic retinopathy was significantly associated with older age (per 1 year: odds ratio [OR], 1.12; 95{\%} confidence interval [CI], 1.07-1.18), female gender (OR, 3.29; 95{\%} CI, 1.09-9.92), and longer axial length (per 1 mm: OR, 4.20; 95{\%} CI, 3.03-5.83). Conclusions: The prevalence of myopic retinopathy was 1.7{\%} in a general Japanese population. Older age, female gender, and longer axial length were significant risk factors for myopic retinopathy. Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article.",
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AU - Yasuda, Miho

AU - Ninomiya, Toshiharu

AU - Noda, Yoshihiro

AU - Arakawa, Satoshi

AU - Hashimoto, Sawako

AU - Ohno-Matsui, Kyoko

AU - Kiyohara, Yutaka

AU - Ishibashi, Tatsuro

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N2 - Purpose: To examine the prevalence of myopic retinopathy and its risk factors in a general Japanese population. Design: Population-based, cross-sectional study. Participants: In 2005, a total of 1969 Hisayama residents aged <40 years consented to participate in this study. Of these, 1892 subjects with adequate data were enrolled. Methods: Each participant underwent comprehensive physical and eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic retinopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, lacquer cracks, or macular atrophy. Main Outcome Measures: Prevalence of myopic retinopathy. Results: Thirty-three participants had myopic retinopathy and the prevalence was 1.7% (2.2% in women and 1.2% in men). The prevalence of myopic retinopathy increased significantly with advancing age. Diffuse chorioretinal atrophy, patchy chorioretinal atrophy, lacquer cracks, and macular atrophy were present in 1.7%, 0.4%, 0.2%, and 0.4% of subjects, respectively. In multivariate analysis, myopic retinopathy was significantly associated with older age (per 1 year: odds ratio [OR], 1.12; 95% confidence interval [CI], 1.07-1.18), female gender (OR, 3.29; 95% CI, 1.09-9.92), and longer axial length (per 1 mm: OR, 4.20; 95% CI, 3.03-5.83). Conclusions: The prevalence of myopic retinopathy was 1.7% in a general Japanese population. Older age, female gender, and longer axial length were significant risk factors for myopic retinopathy. Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article.

AB - Purpose: To examine the prevalence of myopic retinopathy and its risk factors in a general Japanese population. Design: Population-based, cross-sectional study. Participants: In 2005, a total of 1969 Hisayama residents aged <40 years consented to participate in this study. Of these, 1892 subjects with adequate data were enrolled. Methods: Each participant underwent comprehensive physical and eye examinations that included measurements of refractive error, axial lengths, and color fundus photography. Myopic retinopathy was defined as the presence of diffuse chorioretinal atrophy, patchy chorioretinal atrophy, lacquer cracks, or macular atrophy. Main Outcome Measures: Prevalence of myopic retinopathy. Results: Thirty-three participants had myopic retinopathy and the prevalence was 1.7% (2.2% in women and 1.2% in men). The prevalence of myopic retinopathy increased significantly with advancing age. Diffuse chorioretinal atrophy, patchy chorioretinal atrophy, lacquer cracks, and macular atrophy were present in 1.7%, 0.4%, 0.2%, and 0.4% of subjects, respectively. In multivariate analysis, myopic retinopathy was significantly associated with older age (per 1 year: odds ratio [OR], 1.12; 95% confidence interval [CI], 1.07-1.18), female gender (OR, 3.29; 95% CI, 1.09-9.92), and longer axial length (per 1 mm: OR, 4.20; 95% CI, 3.03-5.83). Conclusions: The prevalence of myopic retinopathy was 1.7% in a general Japanese population. Older age, female gender, and longer axial length were significant risk factors for myopic retinopathy. Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article.

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