Prevalence of antibody to Chlamydia pneumoniae in residents of Japan, the Solomon Islands, and Nepal

Chie Shimizu, Shigeki Nabeshima, Kensuke Kikuchi, Norihiro Furusyo, Seizaburo Kashiwagi, Jun Hayashi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Sera of 4,050 residents from Japan, 276 from the Solomon Islands, and 602 from Nepal were tested by an enzyme-linked immunosorbent assay to determine the prevalence of antibody to Chlamydia pneumoniae. The prevalence of IgG and IgA antibodies was significantly higher in the Solomon Islands (64.9% and 82.2%) and Nepal (73.1%, and 69.8%) than in Japan (53.6% and 41.1%). These prevalence rates increased throughout the teenage years in the Solomon Islands and Japan and leveled off with age, whereas in Nepal the prevalence rates gradually increased with age. The prevalence of a high (> 3.0) IgA antibody index, which is suggestive of acute infection, was significantly higher in the Solomon Islands (34.8%) than in Japan (3.2%) and Nepal (10.5%). The prevalence of IgG antibody ranged from 46.4% to 67.7%, and the prevalence of IgA antibody ranged from 33.7% to 61.8% in the four difference areas of Japan. These findings indicate considerable differences in the prevalence of antibodies to C. pneumoniae by age in these nations and between the regions of Japan tested.

Original languageEnglish
Pages (from-to)170-175
Number of pages6
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume67
Issue number2 SUPPL.
Publication statusPublished - Aug 1 2002

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Melanesia
Chlamydophila pneumoniae
Nepal
Japan
Antibodies
Immunoglobulin A
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Shimizu, C., Nabeshima, S., Kikuchi, K., Furusyo, N., Kashiwagi, S., & Hayashi, J. (2002). Prevalence of antibody to Chlamydia pneumoniae in residents of Japan, the Solomon Islands, and Nepal. American Journal of Tropical Medicine and Hygiene, 67(2 SUPPL.), 170-175.

Prevalence of antibody to Chlamydia pneumoniae in residents of Japan, the Solomon Islands, and Nepal. / Shimizu, Chie; Nabeshima, Shigeki; Kikuchi, Kensuke; Furusyo, Norihiro; Kashiwagi, Seizaburo; Hayashi, Jun.

In: American Journal of Tropical Medicine and Hygiene, Vol. 67, No. 2 SUPPL., 01.08.2002, p. 170-175.

Research output: Contribution to journalArticle

Shimizu, C, Nabeshima, S, Kikuchi, K, Furusyo, N, Kashiwagi, S & Hayashi, J 2002, 'Prevalence of antibody to Chlamydia pneumoniae in residents of Japan, the Solomon Islands, and Nepal', American Journal of Tropical Medicine and Hygiene, vol. 67, no. 2 SUPPL., pp. 170-175.
Shimizu C, Nabeshima S, Kikuchi K, Furusyo N, Kashiwagi S, Hayashi J. Prevalence of antibody to Chlamydia pneumoniae in residents of Japan, the Solomon Islands, and Nepal. American Journal of Tropical Medicine and Hygiene. 2002 Aug 1;67(2 SUPPL.):170-175.
Shimizu, Chie ; Nabeshima, Shigeki ; Kikuchi, Kensuke ; Furusyo, Norihiro ; Kashiwagi, Seizaburo ; Hayashi, Jun. / Prevalence of antibody to Chlamydia pneumoniae in residents of Japan, the Solomon Islands, and Nepal. In: American Journal of Tropical Medicine and Hygiene. 2002 ; Vol. 67, No. 2 SUPPL. pp. 170-175.
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