Prevalence of sleep-disordered breathing in Japanese children: efficiency of screening with nocturnal pulse oximetry

Tomoko Nao, Anita Rahmawati, Mari Nishizaka, Hiroyuki Sawatari, Nobuko Moriyama, Akiko Chishaki, Shin Ichi Ando, Tomoko Ohkusa

Research output: Contribution to journalArticle

Abstract

The purposes of this study were: (1) to confirm the prevalence of sleep-disordered breathing (SDB) in Japanese children using nocturnal pulse oximetry (NPOx) as a screening tool and (2) to examine what kind of parameters are suitable for the evaluation of SDB in children. We conducted a study of 99 children between 4 and 15-year-old and obtained their demographic characteristics and the presence of SDB-related symptoms by questionnaire from their parents. In our study, 36% had been Down syndrome (DS), 25% had cardiovascular disease and 34% had dental/oral abnormality. As SDB-related symptoms, snoring (35%), awake disturbance (48%), arousal (41%) and nocturia (19%) were reported. We analyzed each parameter based on the previous reported data of children and temporary defined normal range as follows; 3%ODI < 2.04, 4%ODI < 0.78, SpO2 nadir > 89% and McGill oximetry score = 1. In non-DS group, each parameter showed abnormal value especially in younger group (abnormality; 61–94%), but the abnormality was decreased during the growth (abnormality; 11–63%). Interestingly, in DS group the value of each parameter was kept on abnormal during the growth (abnormality; 55–100%). We investigated the correlation between McGill oximetry score and ODI or SpO2 nadir. There was a significant positive correlation between McGill oximetry score and 3% or 4% ODI. Moreover, there was a significant negative correlation between McGill oximetry score and SpO2 nadir. Based on NPOx screening, prevalence of SDB was high; however, it was decreased during the growth in non-DS group. Each parameter might be useful for SDB screening in children.

Original languageEnglish
Pages (from-to)37-47
Number of pages11
JournalSleep and Biological Rhythms
Volume18
Issue number1
DOIs
Publication statusPublished - Jan 1 2020

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Oximetry
Sleep Apnea Syndromes
Down Syndrome
Mouth Abnormalities
Tooth Abnormalities
Growth
Nocturia
Snoring
Arousal
Reference Values
Cardiovascular Diseases
Parents
Demography

All Science Journal Classification (ASJC) codes

  • Physiology
  • Neuropsychology and Physiological Psychology
  • Neurology
  • Physiology (medical)

Cite this

Prevalence of sleep-disordered breathing in Japanese children : efficiency of screening with nocturnal pulse oximetry. / Nao, Tomoko; Rahmawati, Anita; Nishizaka, Mari; Sawatari, Hiroyuki; Moriyama, Nobuko; Chishaki, Akiko; Ando, Shin Ichi; Ohkusa, Tomoko.

In: Sleep and Biological Rhythms, Vol. 18, No. 1, 01.01.2020, p. 37-47.

Research output: Contribution to journalArticle

Nao, Tomoko ; Rahmawati, Anita ; Nishizaka, Mari ; Sawatari, Hiroyuki ; Moriyama, Nobuko ; Chishaki, Akiko ; Ando, Shin Ichi ; Ohkusa, Tomoko. / Prevalence of sleep-disordered breathing in Japanese children : efficiency of screening with nocturnal pulse oximetry. In: Sleep and Biological Rhythms. 2020 ; Vol. 18, No. 1. pp. 37-47.
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