Primary cardiac synovial sarcoma: A case report and literature review

Yuki Yokouchi, Nobuyuki Hiruta, Toshiaki Oharaseki, Fumie Ihara, Yoshinao Oda, Shingo Ito, Hiromasa Yamashita, Shigeyuki Ozaki, Tatsuya Gomi, Kei Takahashi

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Primary cardiac synovial sarcoma is a rare disease. A 51-year-old man visited our hospital with the chief complaint of palpitations and shortness of breath while exercising. Copious bloody pericardial effusion and a multicystic intrapericardial tumor were detected. A primary cardiac malignant tumor was suspected, an open-chest tumor resection was performed with the objectives of diagnosis and treatment. Histologically, the tumor cells were uniformly spindle-shaped with an ovoid or oval nucleus, they had proliferated in fascicular fashion. In addition myxoid degeneration, a hemangiopericytomatous vascular pattern and pseudorosette formation were seen in some areas of the tumor. Based on the histopathological and immunohistochemical findings and reverse transcription polymerase chain reaction detection of SS18-SSX1 fusion transcripts, a monophasic fibrous type synovial sarcoma was diagnosed. Postoperative radiation therapy was administered and there had been no recurrence 9months after the surgery.

Original languageEnglish
Pages (from-to)150-155
Number of pages6
JournalPathology International
Volume61
Issue number3
DOIs
Publication statusPublished - Mar 1 2011

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Synovial Sarcoma
Neoplasms
Heart Neoplasms
Pericardial Effusion
Rare Diseases
Dyspnea
Reverse Transcription
Blood Vessels
Radiotherapy
Thorax
Recurrence
Polymerase Chain Reaction

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

Cite this

Yokouchi, Y., Hiruta, N., Oharaseki, T., Ihara, F., Oda, Y., Ito, S., ... Takahashi, K. (2011). Primary cardiac synovial sarcoma: A case report and literature review. Pathology International, 61(3), 150-155. https://doi.org/10.1111/j.1440-1827.2010.02631.x

Primary cardiac synovial sarcoma : A case report and literature review. / Yokouchi, Yuki; Hiruta, Nobuyuki; Oharaseki, Toshiaki; Ihara, Fumie; Oda, Yoshinao; Ito, Shingo; Yamashita, Hiromasa; Ozaki, Shigeyuki; Gomi, Tatsuya; Takahashi, Kei.

In: Pathology International, Vol. 61, No. 3, 01.03.2011, p. 150-155.

Research output: Contribution to journalArticle

Yokouchi, Y, Hiruta, N, Oharaseki, T, Ihara, F, Oda, Y, Ito, S, Yamashita, H, Ozaki, S, Gomi, T & Takahashi, K 2011, 'Primary cardiac synovial sarcoma: A case report and literature review', Pathology International, vol. 61, no. 3, pp. 150-155. https://doi.org/10.1111/j.1440-1827.2010.02631.x
Yokouchi, Yuki ; Hiruta, Nobuyuki ; Oharaseki, Toshiaki ; Ihara, Fumie ; Oda, Yoshinao ; Ito, Shingo ; Yamashita, Hiromasa ; Ozaki, Shigeyuki ; Gomi, Tatsuya ; Takahashi, Kei. / Primary cardiac synovial sarcoma : A case report and literature review. In: Pathology International. 2011 ; Vol. 61, No. 3. pp. 150-155.
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