Primary cardiac synovial sarcoma: A case report and literature review

Yuki Yokouchi, Nobuyuki Hiruta, Toshiaki Oharaseki, Fumie Ihara, Yoshinao Oda, Shingo Ito, Hiromasa Yamashita, Shigeyuki Ozaki, Tatsuya Gomi, Kei Takahashi

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)


Primary cardiac synovial sarcoma is a rare disease. A 51-year-old man visited our hospital with the chief complaint of palpitations and shortness of breath while exercising. Copious bloody pericardial effusion and a multicystic intrapericardial tumor were detected. A primary cardiac malignant tumor was suspected, an open-chest tumor resection was performed with the objectives of diagnosis and treatment. Histologically, the tumor cells were uniformly spindle-shaped with an ovoid or oval nucleus, they had proliferated in fascicular fashion. In addition myxoid degeneration, a hemangiopericytomatous vascular pattern and pseudorosette formation were seen in some areas of the tumor. Based on the histopathological and immunohistochemical findings and reverse transcription polymerase chain reaction detection of SS18-SSX1 fusion transcripts, a monophasic fibrous type synovial sarcoma was diagnosed. Postoperative radiation therapy was administered and there had been no recurrence 9months after the surgery.

Original languageEnglish
Pages (from-to)150-155
Number of pages6
JournalPathology International
Issue number3
Publication statusPublished - Mar 2011

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine


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