Primary cutaneous CD30(Ki-1)- positive lymphoma of non-T, non-B origin

Chie Akiyamaa, N. Shibagaki, N. Yasaka, N. Ohtake, Y. Kubota, O. Takayama, R. Katoh, S. Shimada, Masutaka Furue, K. Tamaki

Research output: Contribution to journalArticle

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Abstract

A 71-year-old Japanese woman had two dome-shaped tumors on her right buttock with several surrounding papules. Histological examination revealed that large anaplastic cells and atypical lymphoid cells densely infiltrated the entire dermis. On immunohistochemical examination, Ki-1, HLA-DR. CD25 (IL-2 receptor α), CD122 (IL-2 receptor β). CD4. CD1 lc and CD68 were all positive in the tumor cells, whereas CDIa, CD3, CD5. CD8 and CD 19 were negative. Neither rearrangement of the T-cell receptor β. T-cell receptor γ nor the immunoglobulin heavy-chain was seen. Ultrastructurally, most of the tumor cells contained thick bundles of intermediate filaments in the perinuclear cytoplasm. Thus, this patient was diagnosed as having Ki-1-positive lymphoma of non-T. non-B origin. No recurrence or metastasis of the tumor has been observed in the last 2 years, although surgical resection was required 3 times before control was achieved.

Original languageEnglish
Pages (from-to)238-241
Number of pages4
JournalDermatology
Volume190
Issue number3
DOIs
Publication statusPublished - Jan 1 1995
Externally publishedYes

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Anaplastic Large-Cell Lymphoma
Skin
Interleukin-2 Receptors
T-Cell Antigen Receptor
Neoplasms
Immunoglobulin Heavy Chains
Buttocks
Intermediate Filaments
HLA-DR Antigens
Dermis
Cytoplasm
Lymphocytes
Neoplasm Metastasis
Recurrence

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Akiyamaa, C., Shibagaki, N., Yasaka, N., Ohtake, N., Kubota, Y., Takayama, O., ... Tamaki, K. (1995). Primary cutaneous CD30(Ki-1)- positive lymphoma of non-T, non-B origin. Dermatology, 190(3), 238-241. https://doi.org/10.1159/000246696

Primary cutaneous CD30(Ki-1)- positive lymphoma of non-T, non-B origin. / Akiyamaa, Chie; Shibagaki, N.; Yasaka, N.; Ohtake, N.; Kubota, Y.; Takayama, O.; Katoh, R.; Shimada, S.; Furue, Masutaka; Tamaki, K.

In: Dermatology, Vol. 190, No. 3, 01.01.1995, p. 238-241.

Research output: Contribution to journalArticle

Akiyamaa, C, Shibagaki, N, Yasaka, N, Ohtake, N, Kubota, Y, Takayama, O, Katoh, R, Shimada, S, Furue, M & Tamaki, K 1995, 'Primary cutaneous CD30(Ki-1)- positive lymphoma of non-T, non-B origin', Dermatology, vol. 190, no. 3, pp. 238-241. https://doi.org/10.1159/000246696
Akiyamaa C, Shibagaki N, Yasaka N, Ohtake N, Kubota Y, Takayama O et al. Primary cutaneous CD30(Ki-1)- positive lymphoma of non-T, non-B origin. Dermatology. 1995 Jan 1;190(3):238-241. https://doi.org/10.1159/000246696
Akiyamaa, Chie ; Shibagaki, N. ; Yasaka, N. ; Ohtake, N. ; Kubota, Y. ; Takayama, O. ; Katoh, R. ; Shimada, S. ; Furue, Masutaka ; Tamaki, K. / Primary cutaneous CD30(Ki-1)- positive lymphoma of non-T, non-B origin. In: Dermatology. 1995 ; Vol. 190, No. 3. pp. 238-241.
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