Primary Human Herpesvirus 6 Infection in an Adult

David J. Morris; Anne L. Appleton; Lisbet Sviland; C. A. Schmidt; F. F. Wilborn; W. Siegert; Richard Cone; Lawrence Corey; Robert Hackman; Koichi Akashi; Yoshito Eizuru; Yoshiaki Sumiyoshi

doi:10.1056/NEJM199312093292416

Primary Human Herpesvirus 6 Infection in an Adult

David J. Morris, Anne L. Appleton, Lisbet Sviland, C. A. Schmidt, F. F. Wilborn, W. Siegert, Richard Cone, Lawrence Corey, Robert Hackman, Koichi Akashi, Yoshito Eizuru, Yoshiaki Sumiyoshi

Kyushu University Hospital

Research output: Contribution to journal › Letter › peer-review

2 Citations (Scopus)

Abstract

To the Editor: Akashi et al. (July 15 issue)¹ reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)² detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus¹,³. The authors interpreted the serologic findings (IgG seroconversion with no IgM…

Original language	English
Pages (from-to)	1817-1819
Number of pages	3
Journal	New England Journal of Medicine
Volume	329
Issue number	24
DOIs	https://doi.org/10.1056/NEJM199312093292416
Publication status	Published - Dec 9 1993

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1056/NEJM199312093292416

Cite this

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title = "Primary Human Herpesvirus 6 Infection in an Adult",

abstract = "To the Editor: Akashi et al. (July 15 issue)1 reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)2 detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus1,3. The authors interpreted the serologic findings (IgG seroconversion with no IgM…",

author = "Morris, {David J.} and Appleton, {Anne L.} and Lisbet Sviland and Schmidt, {C. A.} and Wilborn, {F. F.} and W. Siegert and Richard Cone and Lawrence Corey and Robert Hackman and Koichi Akashi and Yoshito Eizuru and Yoshiaki Sumiyoshi",

year = "1993",

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doi = "10.1056/NEJM199312093292416",

language = "English",

volume = "329",

pages = "1817--1819",

journal = "New England Journal of Medicine",

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TY - JOUR

T1 - Primary Human Herpesvirus 6 Infection in an Adult

AU - Morris, David J.

AU - Appleton, Anne L.

AU - Sviland, Lisbet

AU - Schmidt, C. A.

AU - Wilborn, F. F.

AU - Siegert, W.

AU - Cone, Richard

AU - Corey, Lawrence

AU - Hackman, Robert

AU - Akashi, Koichi

AU - Eizuru, Yoshito

AU - Sumiyoshi, Yoshiaki

PY - 1993/12/9

Y1 - 1993/12/9

N2 - To the Editor: Akashi et al. (July 15 issue)1 reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)2 detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus1,3. The authors interpreted the serologic findings (IgG seroconversion with no IgM…

AB - To the Editor: Akashi et al. (July 15 issue)1 reported seroconversion to human herpesvirus 6 (HHV-6) positivity in a patient with an infectious mononucleosis-like syndrome, and Cone et al. (July 15 issue)2 detected high levels of HHV-6 genome in the lungs of recipients of bone marrow transplants who had idiopathic pneumonitis. In neither instance did the data prove that the virus caused the disease being studied. In the first report, the observations could have reflected recurrent HHV-6 infection coincident with signs and symptoms unrelated to the virus1,3. The authors interpreted the serologic findings (IgG seroconversion with no IgM…

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JO - New England Journal of Medicine

JF - New England Journal of Medicine

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ER -

Primary Human Herpesvirus 6 Infection in an Adult

Abstract

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