Primary intracerebral malignant melanoma with leptomeningeal spread, extradural extension and lung metastasis

I. Kobayashi, H. Oka, N. Kawano, A. Kurata, S. Tanaka, S. Utsuki, S. Suzuki, Y. Ishihara, K. Fujii

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6 Citations (Scopus)

Abstract

A rare primary intracerebral solitary malignant melanoma with extracranial metastasis is reported. The patient was a 66-year-old man who was revealed to have a tumor in the right temporal lobe by MRI. The tumor was totally resected and the histopathological diagnosis was malignant melanoma. Despite postoperative treatment with chemo-radiotherapy, tumor recurred with multiple subarachnoid dissemination. Complete autopsy showed marked leptomeningeal dissemination of tumor in the cerebro-spinal compartment. In the outside of the central nervous system, a microscopic metastatic nodule was found in the right lung. Metastatic tumor in the spinal cord showed the extradural extension which might have led to hematogenous metastasis to the lung.

Original languageEnglish
Pages (from-to)43-45
Number of pages3
JournalClinical Neuropathology
Volume20
Issue number1
Publication statusPublished - Feb 13 2001
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Neurology
  • Clinical Neurology

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    Kobayashi, I., Oka, H., Kawano, N., Kurata, A., Tanaka, S., Utsuki, S., Suzuki, S., Ishihara, Y., & Fujii, K. (2001). Primary intracerebral malignant melanoma with leptomeningeal spread, extradural extension and lung metastasis. Clinical Neuropathology, 20(1), 43-45.