Primary malignant lymphoma of the uterine corpus and cervix. Report of a case with immunocytochemical analysis

T. Matsuyama, N. Tsukamoto, Tsunehisa Kaku, K. Matsukuma, T. Hirakawa

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Abstract

In a 69-year-old woman, a gynecologic smear was the first indication of the presence of a nonepithelial malignant tumor. While first thought to represent an adenocarcinoma, malignant lymphoma was later cytologically suspected because of the presence of isolated large malignant cells with macronucleoli. The initial clinical and histologic studies failed to indicate a malignancy. The malignant cells in postoperative tissue samples showed a positive immunohistochemical reaction for leukocyte-common antigen (LCA) and a negative reaction for epithelial membrane antigen, confirming the cytologic suggestion of a uterine lymphoma. Immunocytochemical staining subsequently performed on the destained cytologic specimen gave a positive immunoreactivity to LCA in the cytoplasm of the malignant cells.

Original languageEnglish
Pages (from-to)228-232
Number of pages5
JournalActa Cytologica
Volume33
Issue number2
Publication statusPublished - Jan 1 1989

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Histology

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    Matsuyama, T., Tsukamoto, N., Kaku, T., Matsukuma, K., & Hirakawa, T. (1989). Primary malignant lymphoma of the uterine corpus and cervix. Report of a case with immunocytochemical analysis. Acta Cytologica, 33(2), 228-232.