Primary oral mucormycosis due to rhizopus microsporus after allogeneic stem cell transplantation

Hikaru Sakamoto, Hidehiro Itonaga, Yasushi Sawayama, Jun Taguchi, Tomomi Saijo, Sayaka Kuwatsuka, Mikiko Hashisako, Naoe Kinoshita, Masao Oishi, Hanako Doi, Kosuke Kosai, Katsutaro Nishimoto, Katsumi Tanaka, Katsunori Yanagihara, Hiroshi Mukae, Koichi Izumikawa, Yasushi Miyazaki

Research output: Contribution to journalArticle

Abstract

We herein report a rare case of oral mucormycosis following allogeneic hematopoietic stem cell transplantation. Oral mucormycosis due to Rhizopus microsporus manifested as localized left buccal mucositis with a 1-cm black focus before neutrophil recovery. Combination therapy with liposomal amphotericin B was initiated and surgical debridement was performed; however, the patient died due to progressive generalized mucormycosis. Considerable attention needs to be paid to the diagnosis and management of oral mucormycosis in post-transplant patients, thereby suggesting the importance of fully understanding the risk factors.

Original languageEnglish
Pages (from-to)2567-2571
Number of pages5
JournalInternal Medicine
Volume57
Issue number17
DOIs
Publication statusPublished - Jan 1 2018

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Mucormycosis
Rhizopus
Stem Cell Transplantation
Oral Diagnosis
Mucositis
Cheek
Hematopoietic Stem Cell Transplantation
Debridement
Neutrophils
Transplants

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

Sakamoto, H., Itonaga, H., Sawayama, Y., Taguchi, J., Saijo, T., Kuwatsuka, S., ... Miyazaki, Y. (2018). Primary oral mucormycosis due to rhizopus microsporus after allogeneic stem cell transplantation. Internal Medicine, 57(17), 2567-2571. https://doi.org/10.2169/internalmedicine.0474-17

Primary oral mucormycosis due to rhizopus microsporus after allogeneic stem cell transplantation. / Sakamoto, Hikaru; Itonaga, Hidehiro; Sawayama, Yasushi; Taguchi, Jun; Saijo, Tomomi; Kuwatsuka, Sayaka; Hashisako, Mikiko; Kinoshita, Naoe; Oishi, Masao; Doi, Hanako; Kosai, Kosuke; Nishimoto, Katsutaro; Tanaka, Katsumi; Yanagihara, Katsunori; Mukae, Hiroshi; Izumikawa, Koichi; Miyazaki, Yasushi.

In: Internal Medicine, Vol. 57, No. 17, 01.01.2018, p. 2567-2571.

Research output: Contribution to journalArticle

Sakamoto, H, Itonaga, H, Sawayama, Y, Taguchi, J, Saijo, T, Kuwatsuka, S, Hashisako, M, Kinoshita, N, Oishi, M, Doi, H, Kosai, K, Nishimoto, K, Tanaka, K, Yanagihara, K, Mukae, H, Izumikawa, K & Miyazaki, Y 2018, 'Primary oral mucormycosis due to rhizopus microsporus after allogeneic stem cell transplantation', Internal Medicine, vol. 57, no. 17, pp. 2567-2571. https://doi.org/10.2169/internalmedicine.0474-17
Sakamoto, Hikaru ; Itonaga, Hidehiro ; Sawayama, Yasushi ; Taguchi, Jun ; Saijo, Tomomi ; Kuwatsuka, Sayaka ; Hashisako, Mikiko ; Kinoshita, Naoe ; Oishi, Masao ; Doi, Hanako ; Kosai, Kosuke ; Nishimoto, Katsutaro ; Tanaka, Katsumi ; Yanagihara, Katsunori ; Mukae, Hiroshi ; Izumikawa, Koichi ; Miyazaki, Yasushi. / Primary oral mucormycosis due to rhizopus microsporus after allogeneic stem cell transplantation. In: Internal Medicine. 2018 ; Vol. 57, No. 17. pp. 2567-2571.
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