Primary osteosarcoma of the lung: a case report.

Koji Yamazaki, Kan Okabayashi, Daisuke Hamatake, Shinichi Maekawa, Yasuhiro Yoshida, Ichiro Yoshino, Yoshihiko Maehara

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12 Citations (Scopus)


We report a rare case of primary osteosarcoma of the lung. A 73-year-old Japanese man with a productive cough and hemosputum was referred to us for further evaluation of a huge cavitating mass in the left upper lobe, shown on a radiograph of his chest. The result of a tumor biopsy, via fiberoptic bronchoscope, raised a strong suspicion of sarcoma. Therefore a left upper lobectomy was performed without any adjuvant therapy. The tumor, which measured 72 x 70 x 62 mm, was well-defined, whitish-yellow in color and soft in consistency. Histological examination of the tumor showed a dense proliferation of spindle cells and the presence of many collagen fibers. Eosinophilic osteoid, with no epithelial structures, were noted in the stroma. Immunohistochemically, the tumor cells were positive for mesenchymal, but negative for epithelial markers. These pathological features suggested the tumor was an osteosarcoma. A general inspection of other organs did not reveal any more tumorous lesions, therefore, the final diagnosis of the tumor was primary osteosarcoma of the lung.

Original languageEnglish
Pages (from-to)126-128
Number of pages3
JournalAnnals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia
Issue number2
Publication statusPublished - Apr 2006

All Science Journal Classification (ASJC) codes

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine
  • Gastroenterology


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