Primary rhabdomyosarcoma of the iliac bone in an adult: A case mimicking fibrosarcoma

Yoshinao Oda, Masazumi Tsuneyoshi, Hiroshi Hashimoto, Toshimitsu Iwashita, Masahiro Ushijima, Sachio Masuda, Yukihide Iwamoto, Yoichi Sugioka

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Abstract

Primary rhabdomyosarcoma of bone is exceedingly rare. We present a case of rhabdomyosarcoma of the iliac bone in a 32-year-old male. Histologically, the tumour consisted mainly of a uniform proliferation of elongated spindle cells arranged in a herring bone pattern, simulating fibrosarcoma. Focally there was a conventional embryonal pattern with scattered rhabdomyoblasts possessing an eosinophilic cytoplasm. Immunohistochemical studies disclosed expression of muscle markers such as desmin and muscle-specific actin, in both the embryonal and spindle-cell areas and myoglobin only in the embryonal areas. Such histological features are unusual for classical embryonal rhabdomyosarcoma. The anatomical site and age of the patient are also atypical.

Original languageEnglish
Pages (from-to)65-69
Number of pages5
JournalVirchows Archiv A Pathological Anatomy and Histopathology
Volume423
Issue number1
DOIs
Publication statusPublished - Jan 1 1993

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All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine

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