Abstract
Effects of some organic acids and monoterpenes on production of β-thujaplicin were studied in Cupressus lusitanica suspension cultures. The fungal elicitor-induced biosynthesis of β-thujaplicin was promoted by the feedings of malate, pyruvate, fumarate, succinate, and acetate. These results suggest some relationships between acetate/pyruvate metabolism and β-thujaplicin biosynthesis, or between tricarboxylic acid cycle and β-thujaplicin biosynthesis. Feedings of C. lusitanica suspension cultures with some monoterpenes inhibited elicitor-triggered β-thujaplicin biosynthesis, but 2-carene and terpinyl acetate feedings significantly improved the β-thujaplicin production of C. lusitanica suspension cultures. These results indicate a possible involvement of terpinyl acetate and 2-carene in β-thujaplicin biosynthesis, as well as potential uses of these monoterpenes in large-scale β-thujaplicin production.
| Original language | English |
|---|---|
| Pages (from-to) | 1027-1032 |
| Number of pages | 6 |
| Journal | Bioscience, Biotechnology and Biochemistry |
| Volume | 65 |
| Issue number | 5 |
| DOIs | |
| Publication status | Published - May 2001 |
All Science Journal Classification (ASJC) codes
- Biotechnology
- Analytical Chemistry
- Biochemistry
- Applied Microbiology and Biotechnology
- Molecular Biology
- Organic Chemistry