Prognosis of early-stage part-solid and pure-solid lung adenocarcinomas

Fumihiko Kinoshita, Gouji Toyokawa, Taichi Matsubara, Yuka Kozuma, Naoki Haratake, Shinkichi Takamori, Takaki Akamine, Fumihiko Hirai, Tomoyoshi Takenaka, Tetsuzo Tagawa, Yoshihiko Maehara

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background/Aim: In the new TNM classification (8th edition) of lung cancer, T category is defined based on the solid component size; therefore, part solid type (PST) with and solid type (ST) without ground glass opacity (GGO) are categorized as same T value according to their solid component sizes. However, differences between these tumors have not been clarified. Patients and Methods The study included 274 pStage I lung adenocarcinoma patients who had undergone surgery at our Institution from 2003 to 2012. Their tumors were classified as pure GGO, PST, and ST. After propensity score matching for solid component size, we compared prognoses between PST and ST. Results: The same percentage was noted for PST and ST tumors (119/274; 43.4%). After propensity score matching, the disease-free survival (DFS) was significantly worse in ST than PST (5-year DFS: 69.2% versus 88.7%; p=0.0241). Conclusion: Prognoses of PST and ST adenocarcinomas differ even when their solid component sizes are the same.

Original languageEnglish
Pages (from-to)2665-2670
Number of pages6
JournalAnticancer research
Volume39
Issue number5
DOIs
Publication statusPublished - May 1 2019

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Propensity Score
Disease-Free Survival
Glass
Neoplasms
Neoplasm Staging
Lung Neoplasms
Adenocarcinoma
Adenocarcinoma of lung

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Kinoshita, F., Toyokawa, G., Matsubara, T., Kozuma, Y., Haratake, N., Takamori, S., ... Maehara, Y. (2019). Prognosis of early-stage part-solid and pure-solid lung adenocarcinomas. Anticancer research, 39(5), 2665-2670. https://doi.org/10.21873/anticanres.13391

Prognosis of early-stage part-solid and pure-solid lung adenocarcinomas. / Kinoshita, Fumihiko; Toyokawa, Gouji; Matsubara, Taichi; Kozuma, Yuka; Haratake, Naoki; Takamori, Shinkichi; Akamine, Takaki; Hirai, Fumihiko; Takenaka, Tomoyoshi; Tagawa, Tetsuzo; Maehara, Yoshihiko.

In: Anticancer research, Vol. 39, No. 5, 01.05.2019, p. 2665-2670.

Research output: Contribution to journalArticle

Kinoshita, F, Toyokawa, G, Matsubara, T, Kozuma, Y, Haratake, N, Takamori, S, Akamine, T, Hirai, F, Takenaka, T, Tagawa, T & Maehara, Y 2019, 'Prognosis of early-stage part-solid and pure-solid lung adenocarcinomas', Anticancer research, vol. 39, no. 5, pp. 2665-2670. https://doi.org/10.21873/anticanres.13391
Kinoshita F, Toyokawa G, Matsubara T, Kozuma Y, Haratake N, Takamori S et al. Prognosis of early-stage part-solid and pure-solid lung adenocarcinomas. Anticancer research. 2019 May 1;39(5):2665-2670. https://doi.org/10.21873/anticanres.13391
Kinoshita, Fumihiko ; Toyokawa, Gouji ; Matsubara, Taichi ; Kozuma, Yuka ; Haratake, Naoki ; Takamori, Shinkichi ; Akamine, Takaki ; Hirai, Fumihiko ; Takenaka, Tomoyoshi ; Tagawa, Tetsuzo ; Maehara, Yoshihiko. / Prognosis of early-stage part-solid and pure-solid lung adenocarcinomas. In: Anticancer research. 2019 ; Vol. 39, No. 5. pp. 2665-2670.
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