Prognostic criteria in colorectal carcinoma constructed by the combination of tumor-related and host-related factors

Tadahiro Nozoe, Rumi Matono, Hideki Ijichi, Takefumi Ohga, Takahiro Ezaki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background The significance of prognostic criteria based on a combination of tumor-related and host-related factors for patients with colorectal carcinoma has not been appreciated fully. Methods Correlation of tumor-related and host-related score (TRHRS), which are constructed by the combination of serum elevation of C-reactive protein and pathologic lymph node metastasis (scores ranging 0 to 2), with clinicopathologic features including prognosis was studied in 271 patients with colorectal carcinoma who had been treated with curative resection. Results Significant difference regarding survival was observed both between TRHRS 0 and 1 (P =.028) and between TRHRS 1 and 2 (P <.0001). Multivariate analysis showed that histologic types (P =.040) and TRHRS (P <.0001) were independent prognostic indicators. Conclusion Criteria for the prediction of prognosis in colorectal carcinoma treated with curative resection based on both tumor-related and host-related factors could provide a strict stratification.

Original languageEnglish
Pages (from-to)119-123
Number of pages5
JournalAmerican Journal of Surgery
Volume208
Issue number1
DOIs
Publication statusPublished - Jul 2014

All Science Journal Classification (ASJC) codes

  • Surgery

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