Prognostic factors for noncurative gastric cancer: Univariate and multivariate analyses

Hideo Baba, Toshiro Okuyama, Orita Hiroyuki, Hideaki Anai, Daisuke Korenaga, Yoshihiko Maehara, Kohei Akazawa, Keizo Sugimachi, Walter Lawrence

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Abstract

We performed univariate and multivariate analyses of possible prognostic factors related to postoperative clinical course of patients with advanced gastric cancer. Noncurative resection was done for 119 patients with hepatic metastasis, peritoneal seeding, extensive lymph node metastasis, or direct invasion to adjacent organs, either alone or in various combinations. In the univariate analysis, 6 of 17 items such as peritoneal seeding, lymphatic invasion, vascular invasion, mode of invasion, extent of lymphadenectomy, and width of serosal invasion significantly correlated to the prognosis. The multivariate analysis indicated that three inherent pathologic factors, mode of invasion, lymph node metastasis, and hepatic metastasis, and one treatment factor, extent of lymphadenectomy, were significant variables predictive of the prognosis and that the prognosis was expected to be very poor in cases of infiltrative type, nodal involvement to tertiary nodes, presence of hepatic metastasis, and lymphadenectomy less than R3. Prognosis in terms of the extent of lymphadenectomy shows that extensive lymphadenectomy (R3) proved to be significantly effective in prolonging survival time, even after noncurative gastrectomy. We recommend extensive lymphadenectomy to prolong survival time for such patients. © 1992 Wiley‐Liss, Inc.

Original languageEnglish
Pages (from-to)104-108
Number of pages5
JournalJournal of Surgical Oncology
Volume51
Issue number2
DOIs
Publication statusPublished - Jan 1 1992

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Lymph Node Excision
Stomach Neoplasms
Multivariate Analysis
Neoplasm Metastasis
Liver
Lymph Nodes
Survival
Gastrectomy
Blood Vessels

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology

Cite this

Baba, H., Okuyama, T., Hiroyuki, O., Anai, H., Korenaga, D., Maehara, Y., ... Lawrence, W. (1992). Prognostic factors for noncurative gastric cancer: Univariate and multivariate analyses. Journal of Surgical Oncology, 51(2), 104-108. https://doi.org/10.1002/jso.2930510208

Prognostic factors for noncurative gastric cancer : Univariate and multivariate analyses. / Baba, Hideo; Okuyama, Toshiro; Hiroyuki, Orita; Anai, Hideaki; Korenaga, Daisuke; Maehara, Yoshihiko; Akazawa, Kohei; Sugimachi, Keizo; Lawrence, Walter.

In: Journal of Surgical Oncology, Vol. 51, No. 2, 01.01.1992, p. 104-108.

Research output: Contribution to journalArticle

Baba, H, Okuyama, T, Hiroyuki, O, Anai, H, Korenaga, D, Maehara, Y, Akazawa, K, Sugimachi, K & Lawrence, W 1992, 'Prognostic factors for noncurative gastric cancer: Univariate and multivariate analyses', Journal of Surgical Oncology, vol. 51, no. 2, pp. 104-108. https://doi.org/10.1002/jso.2930510208
Baba, Hideo ; Okuyama, Toshiro ; Hiroyuki, Orita ; Anai, Hideaki ; Korenaga, Daisuke ; Maehara, Yoshihiko ; Akazawa, Kohei ; Sugimachi, Keizo ; Lawrence, Walter. / Prognostic factors for noncurative gastric cancer : Univariate and multivariate analyses. In: Journal of Surgical Oncology. 1992 ; Vol. 51, No. 2. pp. 104-108.
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