Prognostic nutritional index: A tool to predict the biological aggressiveness of gastric carcinoma

Tadahiro Nozoe, Mizuki Ninomiya, Takashi Maeda, Akito Matsukuma, Hideaki Nakashima, Takahiro Ezaki

Research output: Contribution to journalArticle

104 Citations (Scopus)

Abstract

Purpose. The prognostic nutritional index (PNI), which is calculated based on the serum albumin concentration and the peripheral blood lymphocyte count, has been used to assess the immunological and nutritional condition of patients with digestive diseases. However, its value as an indicator of aggressiveness in gastric carcinoma has not been fully investigated. Methods. Two hundred and forty-eight cases of gastric carcinoma were studied with regard to the relationship between the preoperative PNI value and the clinicopathological characteristics of the patients. Results. A lower preoperative PNI value signifi cantly correlated with greater tumor depth, lymph node metastasis, lymphatic permeation, and venous invasion. Moreover, the PNI value proved to be an independent prognostic indicator in gastric carcinoma. Conclusion. The PNI value can be a useful tool to predict the prognosis of patients with gastric carcinoma.

Original languageEnglish
Pages (from-to)440-443
Number of pages4
JournalSurgery today
Volume40
Issue number5
DOIs
Publication statusPublished - May 1 2010

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Nutrition Assessment
Nutritive Value
Stomach
Carcinoma
Lymphatic Metastasis
Lymphocyte Count
Serum Albumin
Lymph Nodes
Neoplasms

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Nozoe, T., Ninomiya, M., Maeda, T., Matsukuma, A., Nakashima, H., & Ezaki, T. (2010). Prognostic nutritional index: A tool to predict the biological aggressiveness of gastric carcinoma. Surgery today, 40(5), 440-443. https://doi.org/10.1007/s00595-009-4065-y

Prognostic nutritional index : A tool to predict the biological aggressiveness of gastric carcinoma. / Nozoe, Tadahiro; Ninomiya, Mizuki; Maeda, Takashi; Matsukuma, Akito; Nakashima, Hideaki; Ezaki, Takahiro.

In: Surgery today, Vol. 40, No. 5, 01.05.2010, p. 440-443.

Research output: Contribution to journalArticle

Nozoe, T, Ninomiya, M, Maeda, T, Matsukuma, A, Nakashima, H & Ezaki, T 2010, 'Prognostic nutritional index: A tool to predict the biological aggressiveness of gastric carcinoma', Surgery today, vol. 40, no. 5, pp. 440-443. https://doi.org/10.1007/s00595-009-4065-y
Nozoe, Tadahiro ; Ninomiya, Mizuki ; Maeda, Takashi ; Matsukuma, Akito ; Nakashima, Hideaki ; Ezaki, Takahiro. / Prognostic nutritional index : A tool to predict the biological aggressiveness of gastric carcinoma. In: Surgery today. 2010 ; Vol. 40, No. 5. pp. 440-443.
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