Prognostic significance of red cell distribution width in hospitalized older patients with heart failure or infection

Keitaro Nakashima, Eiichi Ohgami, Kazuhiko Kato, Souichi Yoshitomi, Toru Maruyama, Mine Harada

Research output: Contribution to journalArticle

Abstract

Aim: Red cell distribution width (RDW) is a simple, sensitive and cost-effective parameter, and is associated with pathophysiology of many common diseases. The aim of the present study was to investigate the prognostic role of RDW in older adults hospitalized for the treatment of heart failure (HF) or infection, because both diseases are fatal, especially in the geriatric population. Methods: This observational study consecutively enrolled 196 Japanese older (aged ≥75 years) patients hospitalized for the treatment of HF (group A, n = 102) or non-cardiovascular bacterial infection (group B, n = 94). Baseline and clinical data were extracted from medical records. The observational period was that of hospitalization. The primary end-point was classified in the order of discharge to the patients’ home, discharge to other facilities and in-hospital death. Results: Longer hospital stay (P < 0.01) and worse prognosis (P < 0.01), including higher in-hospital mortality, were found in patients showing RDW ≥15% relative to those with RDW <15% in both groups. RDW showed no in-hospital variation despite successful treatment of acutely decompensated HF in selected patients of group A (n = 64). Conclusions: The present study showed the role of RDW in predicting the prognostic outcome of older adults hospitalized for the treatment of HF or infection, indicating that RDW is a stable and reliable parameter in these common diseases. Geriatr Gerontol Int 2019; ••: ••–••.

Original languageEnglish
JournalGeriatrics and Gerontology International
DOIs
Publication statusAccepted/In press - Jan 1 2019

Fingerprint

Erythrocyte Indices
Heart Failure
Infection
Treatment Failure
Disease
Group
Patient Discharge
geriatrics
Hospital Mortality
hospitalization
Bacterial Infections
Geriatrics
Medical Records
Observational Studies
Length of Stay
Hospitalization
mortality
death
Costs and Cost Analysis
costs

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • Gerontology
  • Geriatrics and Gerontology

Cite this

Prognostic significance of red cell distribution width in hospitalized older patients with heart failure or infection. / Nakashima, Keitaro; Ohgami, Eiichi; Kato, Kazuhiko; Yoshitomi, Souichi; Maruyama, Toru; Harada, Mine.

In: Geriatrics and Gerontology International, 01.01.2019.

Research output: Contribution to journalArticle

@article{23c25ff2d3004b32a2b737f004cfee8b,
title = "Prognostic significance of red cell distribution width in hospitalized older patients with heart failure or infection",
abstract = "Aim: Red cell distribution width (RDW) is a simple, sensitive and cost-effective parameter, and is associated with pathophysiology of many common diseases. The aim of the present study was to investigate the prognostic role of RDW in older adults hospitalized for the treatment of heart failure (HF) or infection, because both diseases are fatal, especially in the geriatric population. Methods: This observational study consecutively enrolled 196 Japanese older (aged ≥75 years) patients hospitalized for the treatment of HF (group A, n = 102) or non-cardiovascular bacterial infection (group B, n = 94). Baseline and clinical data were extracted from medical records. The observational period was that of hospitalization. The primary end-point was classified in the order of discharge to the patients’ home, discharge to other facilities and in-hospital death. Results: Longer hospital stay (P < 0.01) and worse prognosis (P < 0.01), including higher in-hospital mortality, were found in patients showing RDW ≥15{\%} relative to those with RDW <15{\%} in both groups. RDW showed no in-hospital variation despite successful treatment of acutely decompensated HF in selected patients of group A (n = 64). Conclusions: The present study showed the role of RDW in predicting the prognostic outcome of older adults hospitalized for the treatment of HF or infection, indicating that RDW is a stable and reliable parameter in these common diseases. Geriatr Gerontol Int 2019; ••: ••–••.",
author = "Keitaro Nakashima and Eiichi Ohgami and Kazuhiko Kato and Souichi Yoshitomi and Toru Maruyama and Mine Harada",
year = "2019",
month = "1",
day = "1",
doi = "10.1111/ggi.13755",
language = "English",
journal = "Geriatrics and Gerontology International",
issn = "1447-0594",
publisher = "Japan Geriatrics Society",

}

TY - JOUR

T1 - Prognostic significance of red cell distribution width in hospitalized older patients with heart failure or infection

AU - Nakashima, Keitaro

AU - Ohgami, Eiichi

AU - Kato, Kazuhiko

AU - Yoshitomi, Souichi

AU - Maruyama, Toru

AU - Harada, Mine

PY - 2019/1/1

Y1 - 2019/1/1

N2 - Aim: Red cell distribution width (RDW) is a simple, sensitive and cost-effective parameter, and is associated with pathophysiology of many common diseases. The aim of the present study was to investigate the prognostic role of RDW in older adults hospitalized for the treatment of heart failure (HF) or infection, because both diseases are fatal, especially in the geriatric population. Methods: This observational study consecutively enrolled 196 Japanese older (aged ≥75 years) patients hospitalized for the treatment of HF (group A, n = 102) or non-cardiovascular bacterial infection (group B, n = 94). Baseline and clinical data were extracted from medical records. The observational period was that of hospitalization. The primary end-point was classified in the order of discharge to the patients’ home, discharge to other facilities and in-hospital death. Results: Longer hospital stay (P < 0.01) and worse prognosis (P < 0.01), including higher in-hospital mortality, were found in patients showing RDW ≥15% relative to those with RDW <15% in both groups. RDW showed no in-hospital variation despite successful treatment of acutely decompensated HF in selected patients of group A (n = 64). Conclusions: The present study showed the role of RDW in predicting the prognostic outcome of older adults hospitalized for the treatment of HF or infection, indicating that RDW is a stable and reliable parameter in these common diseases. Geriatr Gerontol Int 2019; ••: ••–••.

AB - Aim: Red cell distribution width (RDW) is a simple, sensitive and cost-effective parameter, and is associated with pathophysiology of many common diseases. The aim of the present study was to investigate the prognostic role of RDW in older adults hospitalized for the treatment of heart failure (HF) or infection, because both diseases are fatal, especially in the geriatric population. Methods: This observational study consecutively enrolled 196 Japanese older (aged ≥75 years) patients hospitalized for the treatment of HF (group A, n = 102) or non-cardiovascular bacterial infection (group B, n = 94). Baseline and clinical data were extracted from medical records. The observational period was that of hospitalization. The primary end-point was classified in the order of discharge to the patients’ home, discharge to other facilities and in-hospital death. Results: Longer hospital stay (P < 0.01) and worse prognosis (P < 0.01), including higher in-hospital mortality, were found in patients showing RDW ≥15% relative to those with RDW <15% in both groups. RDW showed no in-hospital variation despite successful treatment of acutely decompensated HF in selected patients of group A (n = 64). Conclusions: The present study showed the role of RDW in predicting the prognostic outcome of older adults hospitalized for the treatment of HF or infection, indicating that RDW is a stable and reliable parameter in these common diseases. Geriatr Gerontol Int 2019; ••: ••–••.

UR - http://www.scopus.com/inward/record.url?scp=85070317905&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85070317905&partnerID=8YFLogxK

U2 - 10.1111/ggi.13755

DO - 10.1111/ggi.13755

M3 - Article

AN - SCOPUS:85070317905

JO - Geriatrics and Gerontology International

JF - Geriatrics and Gerontology International

SN - 1447-0594

ER -