Programmable protein-protein conjugation via DNA-based self-assembly

Josui Shimada, Tatsuo Maruyama, Momoko Kitaoka, Hisao Yoshinaga, Koji Nakano, Noriho Kamiya, Masahiro Goto

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Protein molecules were precisely arrayed on a designable DNA scaffold close to each other using a DNA aptamer. By adding a chemical cross-linker, the neighboring protein molecules were effectively and covalently cross-linked to each other without losing their activities.

Original languageEnglish
Pages (from-to)6226-6228
Number of pages3
JournalChemical Communications
Volume48
Issue number50
DOIs
Publication statusPublished - May 28 2012

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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