Abstract
The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.
| Original language | English |
|---|---|
| Pages (from-to) | 328-329 |
| Number of pages | 2 |
| Journal | International Congress Series |
| Volume | 1284 |
| DOIs | |
| Publication status | Published - Sep 1 2005 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Medicine(all)
Cite this
Proliferation and adhesion of periodontal ligament cells on synthetic biominerals. / Hatakeyama, Junko; Hatakeyama, Yuji; Takahashi, Ichiro; Suzuki, Osamu; Sasano, Yasuyuki.
In: International Congress Series, Vol. 1284, 01.09.2005, p. 328-329.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Proliferation and adhesion of periodontal ligament cells on synthetic biominerals
AU - Hatakeyama, Junko
AU - Hatakeyama, Yuji
AU - Takahashi, Ichiro
AU - Suzuki, Osamu
AU - Sasano, Yasuyuki
PY - 2005/9/1
Y1 - 2005/9/1
N2 - The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.
AB - The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.
UR - http://www.scopus.com/inward/record.url?scp=33646460930&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33646460930&partnerID=8YFLogxK
U2 - 10.1016/j.ics.2005.06.089
DO - 10.1016/j.ics.2005.06.089
M3 - Review article
VL - 1284
SP - 328
EP - 329
JO - International Congress Series
JF - International Congress Series
SN - 0531-5131
ER -