Proliferation and adhesion of periodontal ligament cells on synthetic biominerals

Junko Hatakeyama; Yuji Hatakeyama; Ichiro Takahashi; Osamu Suzuki; Yasuyuki Sasano

doi:10.1016/j.ics.2005.06.089

Proliferation and adhesion of periodontal ligament cells on synthetic biominerals

Junko Hatakeyama, Yuji Hatakeyama, Ichiro Takahashi, Osamu Suzuki, Yasuyuki Sasano

Research output: Contribution to journal › Review article

Abstract

The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.

Original language	English
Pages (from-to)	328-329
Number of pages	2
Journal	International Congress Series
Volume	1284
DOIs	https://doi.org/10.1016/j.ics.2005.06.089
Publication status	Published - Sep 1 2005
Externally published	Yes

All Science Journal Classification (ASJC) codes

Medicine(all)

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10.1016/j.ics.2005.06.089

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Hatakeyama, J., Hatakeyama, Y., Takahashi, I., Suzuki, O., & Sasano, Y. (2005). Proliferation and adhesion of periodontal ligament cells on synthetic biominerals. International Congress Series, 1284, 328-329. https://doi.org/10.1016/j.ics.2005.06.089

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abstract = "The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.",

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AU - Hatakeyama, Junko

AU - Hatakeyama, Yuji

AU - Takahashi, Ichiro

AU - Suzuki, Osamu

AU - Sasano, Yasuyuki

PY - 2005/9/1

Y1 - 2005/9/1

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AB - The present study was designed to investigate the proliferation and expression of adhesion and extracellular matrix molecules in periodontal ligament (PDL) cells cultured on synthetic calcium phosphates, octacalcium phosphate and its hydrolyzed apatitic product comparing with those cultured on collagen and plastic substrates. Our results suggest that PDL cells expressing various integrins are attached to the synthetic biomineral analogues through collagens and fibronectin produced by themselves. These calcium phosphates relevant to biomineralization may support proliferation and adhesion of PDL cells in vivo.

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