Properties and EPR studies of oligodeoxynucleotides containing 2-N-tert-butylaminoxylpurines.

Mariko Aso; Toshiyuki Kaneko; John Walter Mirc; Noboru Koga; Hiroshi Suemune

Properties and EPR studies of oligodeoxynucleotides containing 2-N-tert-butylaminoxylpurines.

Mariko Aso, Toshiyuki Kaneko, John Walter Mirc, Noboru Koga, Hiroshi Suemune

Chemo-Pharmaceutical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Oligodeoxynucleotide (ODN; 1) containing 2-N-tert-butylaminoxyladenosine (2) was synthesized by the conventional phosphoramidite method. The thermal stability and structure of the duplex of ODN 1 and the complementary strand were elucidated by UV-melting temperature measurements and CD experiments. In phosphate buffer, ODN 1 showed a three line EPR spectrum. Upon duplex formation, the EPR spectrum of 1 changed which indicates that EPR spectra of 1 can provide information on structures of ODN.

Original language	English
Pages (from-to)	3-4
Number of pages	2
Journal	Nucleic acids symposium series (2004)
Issue number	49
Publication status	Published - Jan 1 2005

All Science Journal Classification (ASJC) codes

Medicine(all)

Cite this

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title = "Properties and EPR studies of oligodeoxynucleotides containing 2-N-tert-butylaminoxylpurines.",

abstract = "Oligodeoxynucleotide (ODN; 1) containing 2-N-tert-butylaminoxyladenosine (2) was synthesized by the conventional phosphoramidite method. The thermal stability and structure of the duplex of ODN 1 and the complementary strand were elucidated by UV-melting temperature measurements and CD experiments. In phosphate buffer, ODN 1 showed a three line EPR spectrum. Upon duplex formation, the EPR spectrum of 1 changed which indicates that EPR spectra of 1 can provide information on structures of ODN.",

author = "Mariko Aso and Toshiyuki Kaneko and Mirc, {John Walter} and Noboru Koga and Hiroshi Suemune",

year = "2005",

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AU - Aso, Mariko

AU - Kaneko, Toshiyuki

AU - Mirc, John Walter

AU - Koga, Noboru

AU - Suemune, Hiroshi

PY - 2005/1/1

Y1 - 2005/1/1

N2 - Oligodeoxynucleotide (ODN; 1) containing 2-N-tert-butylaminoxyladenosine (2) was synthesized by the conventional phosphoramidite method. The thermal stability and structure of the duplex of ODN 1 and the complementary strand were elucidated by UV-melting temperature measurements and CD experiments. In phosphate buffer, ODN 1 showed a three line EPR spectrum. Upon duplex formation, the EPR spectrum of 1 changed which indicates that EPR spectra of 1 can provide information on structures of ODN.

AB - Oligodeoxynucleotide (ODN; 1) containing 2-N-tert-butylaminoxyladenosine (2) was synthesized by the conventional phosphoramidite method. The thermal stability and structure of the duplex of ODN 1 and the complementary strand were elucidated by UV-melting temperature measurements and CD experiments. In phosphate buffer, ODN 1 showed a three line EPR spectrum. Upon duplex formation, the EPR spectrum of 1 changed which indicates that EPR spectra of 1 can provide information on structures of ODN.

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AN - SCOPUS:39049184299

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JO - Nucleic acids symposium series (2004)

JF - Nucleic acids symposium series (2004)

IS - 49

ER -

Properties and EPR studies of oligodeoxynucleotides containing 2-N-tert-butylaminoxylpurines.

Abstract

All Science Journal Classification (ASJC) codes

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