Properties of a sucrose-tolerant mutant of Saccharomyces cerevisiae

Takahiro Oba, Hikaru Suenaga, Shigeru Muta, Kosuke Tashiro, Satoru Kuhara

Research output: Contribution to journalArticle

Abstract

We characterized a sucrose-tolerant mutant of Saccharomyces cerevisiae, S22, that produces about four times as much acetate as the wild-type strain K9. We monitored the concentration of extracellular acetate during cultivation, and compared the gene expression ratios of S22 with those of K9 using DNA microarray. We propose that the sucrose tolerance of S22 may be related to the overexpression of the ENA1, ENA2, and ENA5 genes and some cell wall mannoprotein genes, and that the high acetate productivity of S22 is related to the overexpression of the ALD4 gene and oxidative phosphorylation genes.

Original languageEnglish
Pages (from-to)1233-1238
Number of pages6
JournalWorld Journal of Microbiology and Biotechnology
Volume24
Issue number7
DOIs
Publication statusPublished - Jul 1 2008

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Physiology
  • Applied Microbiology and Biotechnology

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