Prophylactic lymph node dissection for early gastric cancer invading submucosa

Yoichi Ikeda, Motonori Saku, Hirofumi Kawanaka, Michiyasu Nonaka, Kohji Yoshida, Yoshihiko Maehara, Keizo Sugimachi

Research output: Contribution to journalArticle

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Abstract

Background/Aims: Prophylactic lymph node dissection for gastric cancer patients was considered to prolong survival time and D2 lymph node dissection was a standard treatment for early gastric cancer invading submucosa without lymph node metastasis. We investigated the possibility of minimizing the extent of prophylactic lymph node dissection for early gastric cancer invading submucosa if there was no evidence of lymph node metastasis. Methodology: We analyzed data on 404 patients with early gastric cancer invading the submucosa who underwent gastrectomy from 1979 to 1998 in the National Kyushu Medical Center, Fukuoka, Japan. The postoperative survival rate of patients with standard D2 dissection was compared with cases of those with limited D2 dissection which was defined as confined as D2 dissection dissections No.7 (lymph nodes were those along the left gastric artery), No.8 (lymph nodes along the anterosuperior common hepatic artery) and No.9 (lymph nodes along the celiac artery). Results: Of the 404 patients, 52 and 17 had lymph node metastasis in group 1 and group 2 nodes, respectively. Of 17 patients with lymph node metastasis in group 2, 14 (82.4%) had metastasis confined to No.7, 8 and 9 of group 2 nodes. The 5-year survival rate of patients with submucosal cancer without lymph node metastasis was 94.4% after limited D2 dissection and 97.3% after standard D2 dissection, respectively. Conclusions: The appropriate prophylactic lymph node dissection for early gastric cancer invading the submucosa without lymph node metastasis was considered to be minimized to limited D2 dissection.

Original languageEnglish
Pages (from-to)887-890
Number of pages4
JournalHepato-gastroenterology
Volume51
Issue number57
Publication statusPublished - May 1 2004

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Lymph Node Excision
Stomach Neoplasms
Lymph Nodes
Dissection
Neoplasm Metastasis
Survival Rate
Celiac Artery
Hepatic Artery
Gastrectomy
Stomach
Japan
Arteries
Survival

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Ikeda, Y., Saku, M., Kawanaka, H., Nonaka, M., Yoshida, K., Maehara, Y., & Sugimachi, K. (2004). Prophylactic lymph node dissection for early gastric cancer invading submucosa. Hepato-gastroenterology, 51(57), 887-890.

Prophylactic lymph node dissection for early gastric cancer invading submucosa. / Ikeda, Yoichi; Saku, Motonori; Kawanaka, Hirofumi; Nonaka, Michiyasu; Yoshida, Kohji; Maehara, Yoshihiko; Sugimachi, Keizo.

In: Hepato-gastroenterology, Vol. 51, No. 57, 01.05.2004, p. 887-890.

Research output: Contribution to journalArticle

Ikeda, Y, Saku, M, Kawanaka, H, Nonaka, M, Yoshida, K, Maehara, Y & Sugimachi, K 2004, 'Prophylactic lymph node dissection for early gastric cancer invading submucosa', Hepato-gastroenterology, vol. 51, no. 57, pp. 887-890.
Ikeda Y, Saku M, Kawanaka H, Nonaka M, Yoshida K, Maehara Y et al. Prophylactic lymph node dissection for early gastric cancer invading submucosa. Hepato-gastroenterology. 2004 May 1;51(57):887-890.
Ikeda, Yoichi ; Saku, Motonori ; Kawanaka, Hirofumi ; Nonaka, Michiyasu ; Yoshida, Kohji ; Maehara, Yoshihiko ; Sugimachi, Keizo. / Prophylactic lymph node dissection for early gastric cancer invading submucosa. In: Hepato-gastroenterology. 2004 ; Vol. 51, No. 57. pp. 887-890.
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AU - Maehara, Yoshihiko

AU - Sugimachi, Keizo

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