Objective: Co-registration between the head shape extracted from anatomical images that are obtained using a 3D digitizer is a non-negligible factor for magnetoencephalographic (MEG) utilization. The study aimed to propose a novel quick system based on a laser scanning technique involving a 3D laser scanner system that allows instant measurement while maintaining high accuracy and reproducibility. Methods: The measurement duration, accuracy, and reproducibility of the finger representations in response to tactile stimulation between the 3D laser scanner-based method and the conventional magnetic field digitizer-based method were compared in 11 healthy subjects. Day-to-day variance in target registration error (TRE), day-to-day and session-to-session variability in head position indicator error (HRE) and source localization accuracy were evaluated with visualization of the source estimation and analysis of variance (ANOVA). Results: Our proposed one-snapshot approach enabled 3D digitization measurements in <5. s, and significantly reduced TRE, while mean HREs were a comparable level. Although there was less dramatic improvement of source localization, we found a significant reduction in session-to-session variability and day-to-day variance using our proposed method. Conclusions: Our results clearly demonstrated improvements in speed, comfort, accuracy, and reproducibility when using our new MEG co-registration method. Significance: A systematic improvement in MEG measurement will be beneficial for routine clinical use.
All Science Journal Classification (ASJC) codes
- Sensory Systems
- Clinical Neurology
- Physiology (medical)