A hot-water extract of tsunomata Chondrus ocellatus was found to contain polysaccharide(s) which showed immunoenhancing activity in fish. In order to identify the effective component, the hot-water extract of tsunomata was fractionated and 0.3 M KCl-insoluble and -soluble fractions (Fractions I and II) were evaluated for their potential to enhance protection against Edwardsiella tarda and Aeromonas hydrophila infections in carp. Intraperitoneal injection of Fraction I (2-3 mg/100g body weight) 6 and 3 days prior to challenge with the pathogenic bacteria resulted in significantly greater survival than that of the control fish. On the other hand, Fraction II was not effective against the pathogenic bacteria at any dose. Chemical and physicochemical analyses revealed that Fraction I was κ-carrageenan containing a trace quantity of ι-carrageenan.
|Number of pages||7|
|Journal||Journal of the Faculty of Agriculture, Kyushu University|
|Publication status||Published - Dec 1997|
All Science Journal Classification (ASJC) codes
- Agricultural and Biological Sciences (miscellaneous)