Protein lipidation catalyzed by microbial transglutaminase

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Abstract

Fattening up: Artificially constructed lipid-protein conjugates can be used to control protein activity and localization at either biological or artificial membrane interfaces. Here, we report a facile technique for the lipid modification of proteins catalyzed by microbial transglutaminase (MTG). MTG-mediated protein lipidation proceeded efficiently without perturbing protein functionality (see figure).

Original languageEnglish
Pages (from-to)14004-14008
Number of pages5
JournalChemistry - A European Journal
Volume17
Issue number50
DOIs
Publication statusPublished - Dec 9 2011

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All Science Journal Classification (ASJC) codes

  • Catalysis
  • Organic Chemistry

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