Protocol for measuring the endurance capacity of mice in an adjustable-current swimming pool

Wataru Mizunoya, Shinichi Oyaizu, Kengo Ishihara, Tohru Fushiki

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

We re-examined the methods used in an adjustable-current swimming pool for evaluating the endurance capacity of mice to improve the sensitivity and reproducibility. We found that the BALB/c strain was most suitable to minimize the variation in time taken to swim to the point of fatigue. We found that precise adjustment of the apparatus and the use of three primary swimming trials to select mice before a study made the swimming time more uniform. This procedure was used to establish a more precise evaluation protocol.

Original languageEnglish
Pages (from-to)1133-1136
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume66
Issue number5
DOIs
Publication statusPublished - Jan 1 2002

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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