Psoriasis

Behind the scenes

Masutaka Furue, Takafumi Kadono

Research output: Contribution to journalReview article

13 Citations (Scopus)

Abstract

Psoriasis is a chronic inflammatory skin disease characterized by a significant deterioration in the quality of life of affected individuals. Notably, psoriasis is significantly associated with cardiovascular and metabolic syndrome and other autoimmune disorders. Recent progress in biologic therapies has revealed the fundamental role of tumor necrosis factor-α, interleukin (IL)-23 and the IL-17A axis together with aberrant overproduction of epidermal IL-36γ in the pathogenesis of psoriasis. This review provides an update on the clinical, pathological and therapeutic advancements involving psoriasis.

Original languageEnglish
Pages (from-to)4-8
Number of pages5
JournalJournal of Dermatology
Volume43
Issue number1
DOIs
Publication statusPublished - Jan 1 2016

Fingerprint

Psoriasis
Metabolic Syndrome X
Interleukin-23
Biological Therapy
Interleukin-17
Interleukins
Skin Diseases
Tumor Necrosis Factor-alpha
Quality of Life
Therapeutics

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Psoriasis : Behind the scenes. / Furue, Masutaka; Kadono, Takafumi.

In: Journal of Dermatology, Vol. 43, No. 1, 01.01.2016, p. 4-8.

Research output: Contribution to journalReview article

Furue, Masutaka ; Kadono, Takafumi. / Psoriasis : Behind the scenes. In: Journal of Dermatology. 2016 ; Vol. 43, No. 1. pp. 4-8.
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