Pyrenylboronic acid as a novel entry for photochemical DNA cleavage

Hikaru Suenaga, Kazuaki Nakashima, Itaru Hamachi, Seiji Shinkai

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

1-Pyrenylboronic acid is bound to supercoiled double strand circular DNA plasmid ColE1 and effects its efficient photocleavage under visible light irradiation: the cleavage reaction, which occurs according to the radical mechanism, can be suppressed by the addition of D-fructose because of boronic acid-saccharide complexation.

Original languageEnglish
Pages (from-to)2479-2482
Number of pages4
JournalTetrahedron Letters
Volume38
Issue number14
DOIs
Publication statusPublished - Apr 7 1997

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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