Pyrolysis gas chromatography mass spectrometry assessment of low-concentration sarcosine in water based samples

Takuma Nozoe, Roman Selyanchyn, Hidetaka Matsui, Seung Woo Lee

Research output: Contribution to journalArticle

Abstract

In this study, Curie point flash pyrolysis gas chromatography mass spectrometry (Py-GC-MS) method was applied for detection of sarcosine in water based samples. Among the variety of sarcosine pyrolysates-two distinguished thermal decomposition compounds were detected with clear chemical pathways (dimethylformamide, DMA, and dimethylacetamide, DMA). The amount of both pyrolysates showed the increase proportional to the initial sarcosine concentration in aqueous samples, and this fact was used for the original compound detection and quantification. Novel and simple sample preparation was applied satisfying the "green chemistry" requirements consisting of drying of aqueous sample in pure helium to remove water. Py-GC-MS analytical method was optimized for the following parameters: volume of the sample and pyrolysis temperature. Matrix influence tests with other amino a ds (methionine, L-alanine, L-cysteine, L-valine, L-leucine, L-threonine, L-lysine, glycine, and L-histidine) and urea were conducted and confirmed the applicability of method for selective detection of sarcosine based on the amount of its pyrolysates DMF and DMA.

Original languageEnglish
Pages (from-to)233-237
Number of pages5
JournalAdvanced Science Letters
Volume19
Issue number1
DOIs
Publication statusPublished - Jan 1 2013
Externally publishedYes

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Sarcosine
Pyrolysis
Gas Chromatography
Mass Spectrometry
Gas chromatography
Gas Chromatography-Mass Spectrometry
pyrolysis
Mass spectrometry
gas chromatography
Dynamic mechanical analysis
mass spectrometry
Water
water
Curie point
thermal decomposition
sample preparation
Dimethylformamide
Helium
helium
urea

All Science Journal Classification (ASJC) codes

  • Computer Science(all)
  • Health(social science)
  • Mathematics(all)
  • Education
  • Environmental Science(all)
  • Engineering(all)
  • Energy(all)

Cite this

Pyrolysis gas chromatography mass spectrometry assessment of low-concentration sarcosine in water based samples. / Nozoe, Takuma; Selyanchyn, Roman; Matsui, Hidetaka; Lee, Seung Woo.

In: Advanced Science Letters, Vol. 19, No. 1, 01.01.2013, p. 233-237.

Research output: Contribution to journalArticle

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