QOL-enhancing surgery for patients with HER2-positive metastatic breast cancer

Masaya Kai, Makoto Kubo, Hitomi Kawaji, Kanako Kurata, Hitomi Mori, Mai Yamada, Masafumi Nakamura

Research output: Contribution to journalArticle

Abstract

The role of the resection of primary tumour in stage IV breast cancer is unclear. Systemic therapy is recommended to prolong the survival and improve the quality of life (QOL). However, even if the systemic therapy is effective to control distant metastasis, sometimes the local lesion worsens, especially in the aggressive subtypes such as HER2-positive breast cancer. In uncontrollable tumours, the wound bed can bleed, weep and get infected, leading to dismal QOL. Our study describes two cases of patients with HER2-positive stage IV breast cancer who underwent palliative mastectomy which resulted in improvement of QOL. Local tumour control through palliative mastectomy can be beneficial for symptomatic aggressive patients with HER2-positive breast cancer to improve their QOL.

Original languageEnglish
JournalBMJ Supportive and Palliative Care
DOIs
Publication statusAccepted/In press - Jan 1 2018

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Quality of Life
Breast Neoplasms
Mastectomy
Neoplasms
Neoplasm Metastasis
Survival
Wounds and Injuries
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • Oncology(nursing)
  • Medical–Surgical

Cite this

QOL-enhancing surgery for patients with HER2-positive metastatic breast cancer. / Kai, Masaya; Kubo, Makoto; Kawaji, Hitomi; Kurata, Kanako; Mori, Hitomi; Yamada, Mai; Nakamura, Masafumi.

In: BMJ Supportive and Palliative Care, 01.01.2018.

Research output: Contribution to journalArticle

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