Quantification of bone volume on radiographs using NIH Image

R. Nagamine, Y. Hanada, M. Kondo, S. Fukumoto, T. Shuto, Yasuharu Nakashima, G. Hirata, A. Katayama, Y. Iwamoto

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

We attempted to quantify periarticular bone atrophy from radiographs of the proximal phalanx in patients with rheumatoid arthritis (RA) by means of the National Institutes of Health (NIH) Image computer program. The degree of brightness or darkness in four squares, each 20 × 20 pixels, in the right third proximal phalanx was measured using NIH Image, and the mean value of the 400 pixels was defined as the brightness/darkness index (BDI). The BDI was used to express bone volume. The BDI value was set at zero for an area of complete darkness and at 255 for an area of maximum brightness. The mean coefficient of variation in our hospital was 2.28%. The BDI was measured in 54 RA patients and 146 normal volunteers. The mean BDI at the midpoint of the diaphysis was 100 in RA patients and 176 in normal volunteers, while at the medial side of the proximal end it was 75 and 145, respectively. The difference between normal volunteers and RA patients was greatest in younger people. In some young RA patients, the BDI was significantly low at the medial side of the proximal end, clearly demonstrating periarticular bone atrophy. Periarticular bone atrophy can be quantified using the NIH Image computer program.

Original languageEnglish
Pages (from-to)220-224
Number of pages5
JournalModern Rheumatology
Volume10
Issue number4
DOIs
Publication statusPublished - Jan 12 2000

Fingerprint

Darkness
National Institutes of Health (U.S.)
Bone and Bones
Rheumatoid Arthritis
Atrophy
Healthy Volunteers
Software
Diaphyses

All Science Journal Classification (ASJC) codes

  • Rheumatology

Cite this

Nagamine, R., Hanada, Y., Kondo, M., Fukumoto, S., Shuto, T., Nakashima, Y., ... Iwamoto, Y. (2000). Quantification of bone volume on radiographs using NIH Image. Modern Rheumatology, 10(4), 220-224. https://doi.org/10.3109/s101650070006

Quantification of bone volume on radiographs using NIH Image. / Nagamine, R.; Hanada, Y.; Kondo, M.; Fukumoto, S.; Shuto, T.; Nakashima, Yasuharu; Hirata, G.; Katayama, A.; Iwamoto, Y.

In: Modern Rheumatology, Vol. 10, No. 4, 12.01.2000, p. 220-224.

Research output: Contribution to journalArticle

Nagamine, R, Hanada, Y, Kondo, M, Fukumoto, S, Shuto, T, Nakashima, Y, Hirata, G, Katayama, A & Iwamoto, Y 2000, 'Quantification of bone volume on radiographs using NIH Image', Modern Rheumatology, vol. 10, no. 4, pp. 220-224. https://doi.org/10.3109/s101650070006
Nagamine R, Hanada Y, Kondo M, Fukumoto S, Shuto T, Nakashima Y et al. Quantification of bone volume on radiographs using NIH Image. Modern Rheumatology. 2000 Jan 12;10(4):220-224. https://doi.org/10.3109/s101650070006
Nagamine, R. ; Hanada, Y. ; Kondo, M. ; Fukumoto, S. ; Shuto, T. ; Nakashima, Yasuharu ; Hirata, G. ; Katayama, A. ; Iwamoto, Y. / Quantification of bone volume on radiographs using NIH Image. In: Modern Rheumatology. 2000 ; Vol. 10, No. 4. pp. 220-224.
@article{7fb925a3e9714a9a857d30377789a89b,
title = "Quantification of bone volume on radiographs using NIH Image",
abstract = "We attempted to quantify periarticular bone atrophy from radiographs of the proximal phalanx in patients with rheumatoid arthritis (RA) by means of the National Institutes of Health (NIH) Image computer program. The degree of brightness or darkness in four squares, each 20 × 20 pixels, in the right third proximal phalanx was measured using NIH Image, and the mean value of the 400 pixels was defined as the brightness/darkness index (BDI). The BDI was used to express bone volume. The BDI value was set at zero for an area of complete darkness and at 255 for an area of maximum brightness. The mean coefficient of variation in our hospital was 2.28{\%}. The BDI was measured in 54 RA patients and 146 normal volunteers. The mean BDI at the midpoint of the diaphysis was 100 in RA patients and 176 in normal volunteers, while at the medial side of the proximal end it was 75 and 145, respectively. The difference between normal volunteers and RA patients was greatest in younger people. In some young RA patients, the BDI was significantly low at the medial side of the proximal end, clearly demonstrating periarticular bone atrophy. Periarticular bone atrophy can be quantified using the NIH Image computer program.",
author = "R. Nagamine and Y. Hanada and M. Kondo and S. Fukumoto and T. Shuto and Yasuharu Nakashima and G. Hirata and A. Katayama and Y. Iwamoto",
year = "2000",
month = "1",
day = "12",
doi = "10.3109/s101650070006",
language = "English",
volume = "10",
pages = "220--224",
journal = "Modern Rheumatology",
issn = "1439-7595",
publisher = "Springer Japan",
number = "4",

}

TY - JOUR

T1 - Quantification of bone volume on radiographs using NIH Image

AU - Nagamine, R.

AU - Hanada, Y.

AU - Kondo, M.

AU - Fukumoto, S.

AU - Shuto, T.

AU - Nakashima, Yasuharu

AU - Hirata, G.

AU - Katayama, A.

AU - Iwamoto, Y.

PY - 2000/1/12

Y1 - 2000/1/12

N2 - We attempted to quantify periarticular bone atrophy from radiographs of the proximal phalanx in patients with rheumatoid arthritis (RA) by means of the National Institutes of Health (NIH) Image computer program. The degree of brightness or darkness in four squares, each 20 × 20 pixels, in the right third proximal phalanx was measured using NIH Image, and the mean value of the 400 pixels was defined as the brightness/darkness index (BDI). The BDI was used to express bone volume. The BDI value was set at zero for an area of complete darkness and at 255 for an area of maximum brightness. The mean coefficient of variation in our hospital was 2.28%. The BDI was measured in 54 RA patients and 146 normal volunteers. The mean BDI at the midpoint of the diaphysis was 100 in RA patients and 176 in normal volunteers, while at the medial side of the proximal end it was 75 and 145, respectively. The difference between normal volunteers and RA patients was greatest in younger people. In some young RA patients, the BDI was significantly low at the medial side of the proximal end, clearly demonstrating periarticular bone atrophy. Periarticular bone atrophy can be quantified using the NIH Image computer program.

AB - We attempted to quantify periarticular bone atrophy from radiographs of the proximal phalanx in patients with rheumatoid arthritis (RA) by means of the National Institutes of Health (NIH) Image computer program. The degree of brightness or darkness in four squares, each 20 × 20 pixels, in the right third proximal phalanx was measured using NIH Image, and the mean value of the 400 pixels was defined as the brightness/darkness index (BDI). The BDI was used to express bone volume. The BDI value was set at zero for an area of complete darkness and at 255 for an area of maximum brightness. The mean coefficient of variation in our hospital was 2.28%. The BDI was measured in 54 RA patients and 146 normal volunteers. The mean BDI at the midpoint of the diaphysis was 100 in RA patients and 176 in normal volunteers, while at the medial side of the proximal end it was 75 and 145, respectively. The difference between normal volunteers and RA patients was greatest in younger people. In some young RA patients, the BDI was significantly low at the medial side of the proximal end, clearly demonstrating periarticular bone atrophy. Periarticular bone atrophy can be quantified using the NIH Image computer program.

UR - http://www.scopus.com/inward/record.url?scp=84879630690&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84879630690&partnerID=8YFLogxK

U2 - 10.3109/s101650070006

DO - 10.3109/s101650070006

M3 - Article

VL - 10

SP - 220

EP - 224

JO - Modern Rheumatology

JF - Modern Rheumatology

SN - 1439-7595

IS - 4

ER -