Quantitative and pattern analyses of continuous-wave doppler-derived pulmonary regurgitant flow velocity for the diagnosis of constrictive pericarditis

Sanae Kaga, Taisei Mikami, Yuka Takamatsu, Ayumu Abe, Kazunori Okada, Masahiro Nakabachi, Hisao Nishino, Shinobu Yokoyama, Mutsumi Nishida, Chikara Shimizu, Hiroyuki Iwano, Satoshi Yamada, Hiroyuki Tsutsui

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Abstract

Conclusions The quantitative and pattern analyses of continuous-wave Doppler-derived pulmonary regurgitation velocity could enhance the accuracy of echocardiographic detection of CP.

Methods Fifteen patients with CP, 18 patients with restrictive cardiomyopathy, and 20 normal subjects were studied retrospectively. Using continuous-wave Doppler echocardiography, pulmonary regurgitation velocities were measured at the early diastolic peak (VMAx), mid-diastolic inflection point (VIFL), and late diastolic minimal point (VMIN).

Results VIFL, VIFL/VMAx, VMIN, and VMIN/VMAx were significantly lower in the CP group compared with the restrictive cardiomyopathy and normal groups. Prevalence rates of patients with early mid-diastolic inflection, VIFL/VMAx < 0.5, VMIN < 50 cm/sec, and VMIN/VMAx < 0.33 were significantly greater in the CP group compared with the other groups. Sensitivity and specificity for the diagnosis of CP were 93% and 74%, respectively, for the presence of early mid-diastolic inflection, 73% and 100% for VIFL/VMAx < 0.5, 73% and 97% for VMIN < 50 cm/sec, and 93% and 92% for VMIN/VMAx < 0.33.

Background Many echocardiographic features of constrictive pericarditis (CP) have been reported, but each alone has a limitation either in sensitivity or in specificity. Continuous-wave Doppler-derived flow velocity of pulmonary regurgitation can reflect the diastolic right ventricular pressure pattern characteristic of CP and be useful for its detection.

Original languageEnglish
Pages (from-to)1223-1229
Number of pages7
JournalJournal of the American Society of Echocardiography
Volume27
Issue number11
DOIs
Publication statusPublished - Nov 1 2014
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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    Kaga, S., Mikami, T., Takamatsu, Y., Abe, A., Okada, K., Nakabachi, M., Nishino, H., Yokoyama, S., Nishida, M., Shimizu, C., Iwano, H., Yamada, S., & Tsutsui, H. (2014). Quantitative and pattern analyses of continuous-wave doppler-derived pulmonary regurgitant flow velocity for the diagnosis of constrictive pericarditis. Journal of the American Society of Echocardiography, 27(11), 1223-1229. https://doi.org/10.1016/j.echo.2014.07.002