Quantitative evaluation of insulating performance on silicon nanobiodevices for fully integrated nanopore single DNA sequencing

Mamiko Sano, Takao Yasui, Noritada Kaji, Masateru Taniguchi, Tomoji Kawai, Yoshinobu Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

To realize a silicon-based semiconductor nanopore DNA sequencer, we have quantitatively evaluated insulating performance of silicon-based nanoslit array structures to stretch a random-coiled DNA molecule by electrokinetic force as a step prior to nanopore DNA sequencing. We found critical electric fields which trigger electric breakdown as a function of buffer concentration and successfully observed a single DNA molecular stretching in the nanoslit array structures under the explored conditions.

Original languageEnglish
Title of host publication18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
PublisherChemical and Biological Microsystems Society
Pages1479-1481
Number of pages3
ISBN (Electronic)9780979806476
Publication statusPublished - Jan 1 2014
Externally publishedYes
Event18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, United States
Duration: Oct 26 2014Oct 30 2014

Other

Other18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014
CountryUnited States
CitySan Antonio
Period10/26/1410/30/14

All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Fingerprint Dive into the research topics of 'Quantitative evaluation of insulating performance on silicon nanobiodevices for fully integrated nanopore single DNA sequencing'. Together they form a unique fingerprint.

  • Cite this

    Sano, M., Yasui, T., Kaji, N., Taniguchi, M., Kawai, T., & Baba, Y. (2014). Quantitative evaluation of insulating performance on silicon nanobiodevices for fully integrated nanopore single DNA sequencing. In 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 (pp. 1479-1481). Chemical and Biological Microsystems Society.