Quantitative Evaluation of the Robustness of Beam Directions Based on Power Spectral Analysis of Water-Equivalent Path Length Image in Charged Particle Therapy

Hidetaka Arimura, Genyu Kakiuchi, Yoshiyuki Shioyama, Shin Ichi Minohara, Takahiro Nakamoto, Katsumasa Nakamura, Hiroshi Honda, Mutsumi Tashiro, Tatsuaki Kanai, Hideki Hirata

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Objective: To investigate the quantitative evaluation of the robustness of particle beam directions against patient setup errors in charged particle therapy. Methods: Power spectral analysis of target water-equivalent path length (WEPL) images in beam's eye views was employed for quantitative evaluation of the robustness of beam directions. The relationship between the beam direction and the 0th moment of the power spectrum was calculated for estimating the robustness of each beam direction. We applied the proposed evaluation method to 7 head-region cancer patients. Results: The mean of the 0th moment at the conventional beam directions, which were empirically selected by a manual method, was smaller than that for the avoided beam directions with a statistically significant difference (p < 0.05), which means that the conventional beam directions were appropriate from the theoretical point of view. Conclusions: The results in this preliminary study may lead to quantitative selection of beam directions based on the relationship between the beam direction and the 0th moment derived from the target WEPL image in charged particle therapy.

Original languageEnglish
Pages (from-to)1-16
Number of pages16
JournalInternational Journal of Intelligent Computing in Medical Sciences and Image Processing
Volume6
Issue number1
DOIs
Publication statusPublished - Jan 2014

All Science Journal Classification (ASJC) codes

  • Computer Science(all)
  • Radiology Nuclear Medicine and imaging

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