Quantitative measurement of protein using metal mesh device

Seiji Kamba, Hirokazu Seto, Takashi Kondo, Yoshiko Miura

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Biosensing of protein adsorption with metal mesh device (MMD) was investigated by computational calculations and experiments. Electromagnetic field computation was carried out with a single unit cell of MMD. Equivalent circuit model of MMD on the single unit cell was assumed, and the biosensing with MMD was analyzed in detail by computational calculation and experimental measurements. The dip frequency of MMD was shifted by adsorption of protein on MMD. The shift of dip frequency of MMD was proportional to the amount of protein adsorption. The sensitivity of MMD biosensing was dependent on the microstructure of MMD, and proportional to the square of the dip frequency. The refinement of MMD structure can improve the sensitivity of protein detection.

Original languageEnglish
Pages (from-to)1033-1039
Number of pages7
Journalanalytical sciences
Volume33
Issue number9
DOIs
Publication statusPublished - Jan 1 2017

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

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