Radiotherapy for localized relapse in patients with non-Hodgkin's lymphoma: A preliminary report

K. Nakamura, N. Kunitake, M. Kimura, Y. Shioyama, H. Terashima, K. Masuda

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Abstract

Purpose: To evaluate the usefulness of radiotherapy for relapse of non-Hodgkin's lymphoma (NHL) at a localized site. Methods: Of 79 patients with relapsed intermediate- or high-grade NHL, 13 patients (16.5%) with a localized relapse were analyzed retrospectively. Results: Five patients were treated with radiotherapy alone and eight were treated with radiotherapy plus conventional chemotherapy (CHOP or other combinations). Radiotherapy was delivered to the involved field to a mean total dose of 34.1 Gy (range, 21-51 Gy). The 5-year overall and disease-free survival rates were 80.2% and 76.2%, respectively. Four patients relapsed subsequently. After further salvage therapy, two patients died of NHL and two were alive without active disease. Conclusion: Radiotherapy may be an important component of treatment for selected patients with NHL who relapse at a localized site.

Original languageEnglish
Pages (from-to)245-248
Number of pages4
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Volume18
Issue number4
Publication statusPublished - Sep 25 2000

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All Science Journal Classification (ASJC) codes

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Oncology

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