Abstract
We evaluated the efficacy of salvage external beam radiotherapy (RT) to the prostate bed for men with prostate-specific antigen (PSA) failure following radical prostatectomy. Fourteen patients underwent RT for PSA failure following radical prostatectomy between 1999 and 2000. Median follow-up was 24 months. Median PSA level before RT was 0.51 ng/ml. Radiation dose was 60Gy or 61.4Gy. The 3-year actuarial biochemical disease-free survival (bDFS) rate was 40%. The biochemical effectiveness of RT was better in cases with a PSA level of less than 1 ng/ml compared to that in cases with a level higher than 1 ng/ml. The PSA level before RT and surgical margin involvement were identified as prognostic factors for bDFS. No patients experienced grade 3 toxicity. RT for PSA failure following radical prostatectomy seems to be very effective and was only slightly toxic during a limited follow-up period.
Original language | English |
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Pages (from-to) | 130-134 |
Number of pages | 5 |
Journal | Nishinihon Journal of Urology |
Volume | 69 |
Issue number | 3 |
Publication status | Published - Mar 1 2007 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Urology