Randomized prospective evaluation of adjuvant hyaluronic acid therapy administered after knee arthroscopy.

Geoffrey Westrich, Sarah Schaefer, Sarah Walcott-Sapp, Leonard Lyman Stephen

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Intra-articular injections of hyaluronic acid products may eliminate pain, improve mobility and quality of life, and delay osteoarthritis progression. In this study, we evaluated the safety and efficacy of sodium hyaluronate injections given after knee arthroscopy. Forty-six patients with early osteoarthritis and a symptomatic meniscus tear were prospectively randomized into study (injection) and control groups and underwent knee arthroscopy. Study patients received 3 sodium hyaluronate injections after surgery. Study and control outcomes were compared 3 and 6 months after surgery. The injection patients had significantly less pain (visual analog scale) at 3-month follow-up and more flexion at 6-month follow-up. Tenderness, pain on motion, and crepitus were significantly more likely to be absent from injection patients at the 3- and 6-month follow-ups. Patients with osteoarthritis and a symptomatic meniscus tear may experience more pain relief and functional mobility after arthroscopic surgery plus hyaluronic acid injections than after arthroscopy alone.

Original languageEnglish
Pages (from-to)612-616
Number of pages5
JournalAmerican journal of orthopedics (Belle Mead, N.J.)
Volume38
Issue number12
Publication statusPublished - Jan 1 2009
Externally publishedYes

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Arthroscopy
Hyaluronic Acid
Knee
Injections
Osteoarthritis
Pain
Therapeutics
Intra-Articular Injections
Pain Measurement
Quality of Life
Outcome Assessment (Health Care)
Safety
Control Groups

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Randomized prospective evaluation of adjuvant hyaluronic acid therapy administered after knee arthroscopy. / Westrich, Geoffrey; Schaefer, Sarah; Walcott-Sapp, Sarah; Lyman Stephen, Leonard.

In: American journal of orthopedics (Belle Mead, N.J.), Vol. 38, No. 12, 01.01.2009, p. 612-616.

Research output: Contribution to journalArticle

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