TY - JOUR
T1 - Rapid awareness and transmission of severe acute respiratory syndrome in Hanoi French Hospital, Vietnam
AU - Nishiura, Hiroshi
AU - Kuratsuji, Tadatoshi
AU - Quy, Tran
AU - Phi, Nguyen Chi
AU - Van Ban, Vo
AU - Ha, Le Dang
AU - Long, Hoang Thuy
AU - Yanai, Hideki
AU - Keicho, Naoto
AU - Kirikae, Teruo
AU - Sasazuki, Takehiko
AU - Anderson, Roy M.
PY - 2005/7
Y1 - 2005/7
N2 - A case-control study was conducted to examine the relationship between severe acute respiratory syndrome (SARS) and the time-dependent precautionary behaviors taken during an outbreak of SARS in Hanoi French Hospital (HFH), Vietnam. Masks (odds ratio [OR] = 0.3; 95% confidence interval [CI]: 0.1, 0.7) and gowns (OR = 0.2; 95% CI: 0.0, 0.8) appeared to prevent SARS transmission. The proportion of doctors and nurses who undertook each measure significantly improved (χ2 = 9.8551, P = 0.043) after the onset of secondary cases. The impact of individual behaviors on an outbreak was investigated through mathematical approaches. The reproduction number decreased from 4.1 to 0.7 after notification. The basic reproduction number was estimated, and the use of masks alone was shown to be insufficient in containing an epidemic. Intuitive results obtained by means of stochastic individual-based simulations showed that rapid improvements in behavior and isolation would increase the probability of extinction.
AB - A case-control study was conducted to examine the relationship between severe acute respiratory syndrome (SARS) and the time-dependent precautionary behaviors taken during an outbreak of SARS in Hanoi French Hospital (HFH), Vietnam. Masks (odds ratio [OR] = 0.3; 95% confidence interval [CI]: 0.1, 0.7) and gowns (OR = 0.2; 95% CI: 0.0, 0.8) appeared to prevent SARS transmission. The proportion of doctors and nurses who undertook each measure significantly improved (χ2 = 9.8551, P = 0.043) after the onset of secondary cases. The impact of individual behaviors on an outbreak was investigated through mathematical approaches. The reproduction number decreased from 4.1 to 0.7 after notification. The basic reproduction number was estimated, and the use of masks alone was shown to be insufficient in containing an epidemic. Intuitive results obtained by means of stochastic individual-based simulations showed that rapid improvements in behavior and isolation would increase the probability of extinction.
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U2 - 10.4269/ajtmh.2005.73.17
DO - 10.4269/ajtmh.2005.73.17
M3 - Article
C2 - 16014825
AN - SCOPUS:24644431988
SN - 0002-9637
VL - 73
SP - 17
EP - 25
JO - American Journal of Tropical Medicine and Hygiene
JF - American Journal of Tropical Medicine and Hygiene
IS - 1
ER -
