Real-time and the in vivo detection of minute cancer invasion to the portal-superior mesenteric vein using contact endoscopy during a pancreatic cancer resection

Hidetoshi Eguchi, Osamu Ishikawa, Hiroaki Ohigashi, Hidenori Takahashi, Masayuki Ohue, Akemi Takenaka, Yasuhiko Tomita, Masahiko Yano

Research output: Contribution to journalArticle

Abstract

The portal-superior mesenteric vein (PV/SMV) is occasionally involved by a microscopic level of cancer invasion from pancreatic cancer even when it seems to be intact by a macroscopic inspection during surgery. Therefore, contact endoscopy, with which a high-magnification image of the methylene blue-stained PV/SMV wall can be obtained in vivo, was used during pancreatic cancer resections. Contact endoscopy succeeded in detecting minute cancer invasion and identified the precise location on the isolated PV/SMV wall in 3 out of 11 patients whose PV/SMVs had been disclosed from the pancreatic tumors. The 3 positive patients underwent an additional resection of the PV/SMV, and appropriate ranges of PV/SMV resection were confirmed by the postoperative histology. Thus, contact endoscopy is considered a promising modality for making a real-time diagnosis on the precise location of minute cancer, without requiring any tissue sampling.

Original languageEnglish
JournalAmerican Journal of Surgery
Volume198
Issue number5
DOIs
Publication statusPublished - Nov 1 2009

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Mesenteric Veins
Pancreatic Neoplasms
Endoscopy
Neoplasms
Methylene Blue
Histology

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Real-time and the in vivo detection of minute cancer invasion to the portal-superior mesenteric vein using contact endoscopy during a pancreatic cancer resection. / Eguchi, Hidetoshi; Ishikawa, Osamu; Ohigashi, Hiroaki; Takahashi, Hidenori; Ohue, Masayuki; Takenaka, Akemi; Tomita, Yasuhiko; Yano, Masahiko.

In: American Journal of Surgery, Vol. 198, No. 5, 01.11.2009.

Research output: Contribution to journalArticle

Eguchi, Hidetoshi ; Ishikawa, Osamu ; Ohigashi, Hiroaki ; Takahashi, Hidenori ; Ohue, Masayuki ; Takenaka, Akemi ; Tomita, Yasuhiko ; Yano, Masahiko. / Real-time and the in vivo detection of minute cancer invasion to the portal-superior mesenteric vein using contact endoscopy during a pancreatic cancer resection. In: American Journal of Surgery. 2009 ; Vol. 198, No. 5.
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AU - Takahashi, Hidenori

AU - Ohue, Masayuki

AU - Takenaka, Akemi

AU - Tomita, Yasuhiko

AU - Yano, Masahiko

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