Real-time observation of dna comformational transitions at a single-molecule level by microfluidic devices

H. Suzuki, N. Kaji, Y. Okamoto, M. Tokeshi, Y. Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We have developed a precise fluid control and a solution exchange system by a combination of novel microchannel designs and electroosmotic pumps for real-time observation of DNA conformational transitions at a single-molecule level. By using the microfluidic devices, we revealed the stepwise conformational transitions induced by ethanol solution.

Original languageEnglish
Title of host publication14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Pages1880-1882
Number of pages3
Publication statusPublished - Dec 1 2010
Externally publishedYes
Event14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 - Groningen, Netherlands
Duration: Oct 3 2010Oct 7 2010

Publication series

Name14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
Volume3

Other

Other14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010
CountryNetherlands
CityGroningen
Period10/3/1010/7/10

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All Science Journal Classification (ASJC) codes

  • Control and Systems Engineering

Cite this

Suzuki, H., Kaji, N., Okamoto, Y., Tokeshi, M., & Baba, Y. (2010). Real-time observation of dna comformational transitions at a single-molecule level by microfluidic devices. In 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010 (pp. 1880-1882). (14th International Conference on Miniaturized Systems for Chemistry and Life Sciences 2010, MicroTAS 2010; Vol. 3).