Recent advances in the pathogenesis of hyper IgE syndrome

Hidetoshi Takada, Yoshiyuki Minegishi

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

Hyperimmunoglobulin-E syndrome (HIES) is one of the primary immunodeficiency with the manifestations of recurrent infections especially with Staphylococcus aureus, characteristic facies, hyperextensibility of joints, multiple bone fractures, scoliosis, and delayed shedding of the primary teeth. It is a multisystem disease of autosomal dominant or recessive inheritance. Recently, the genetic causes of HIES (STAT3, TYK2, and DOCK8) were clarified.

Original languageEnglish
Pages (from-to)15-19
Number of pages5
JournalJapanese Journal of Clinical Immunology
Volume33
Issue number1
DOIs
Publication statusPublished - Mar 5 2010

Fingerprint

Job Syndrome
Deciduous Tooth
Bone Fractures
Scoliosis
Staphylococcus aureus
Joints
Infection

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

Cite this

Recent advances in the pathogenesis of hyper IgE syndrome. / Takada, Hidetoshi; Minegishi, Yoshiyuki.

In: Japanese Journal of Clinical Immunology, Vol. 33, No. 1, 05.03.2010, p. 15-19.

Research output: Contribution to journalReview article

Takada, Hidetoshi ; Minegishi, Yoshiyuki. / Recent advances in the pathogenesis of hyper IgE syndrome. In: Japanese Journal of Clinical Immunology. 2010 ; Vol. 33, No. 1. pp. 15-19.
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