Abstract
Hyperimmunoglobulin-E syndrome (HIES) is one of the primary immunodeficiency with the manifestations of recurrent infections especially with Staphylococcus aureus, characteristic facies, hyperextensibility of joints, multiple bone fractures, scoliosis, and delayed shedding of the primary teeth. It is a multisystem disease of autosomal dominant or recessive inheritance. Recently, the genetic causes of HIES (STAT3, TYK2, and DOCK8) were clarified.
Original language | English |
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Pages (from-to) | 15-19 |
Number of pages | 5 |
Journal | Japanese Journal of Clinical Immunology |
Volume | 33 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2010 |
All Science Journal Classification (ASJC) codes
- Immunology and Allergy
- Immunology