Recent advances in the understanding of the induction and regulation of mucosal inflammation

Warren Strober, Ivan J. Fuss, Kazuhiko Nakamura, Atsushi Kitani

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

In summary, it is quite apparent that the TNBS colitis model has yielded many important new insights into the mechanisms underlying mucosal inflammation. Perhaps the most important of these is the concept that the presence or absence of inflammation depends on the presence of a robust regulatory system in which cells producing suppressor cytokines modified and down-regulated effector cell responses that would otherwise lead to inflammation. Attempts to harness this regulatory response in the therapy of IBD are now ongoing.

Original languageEnglish
Pages (from-to)55-58
Number of pages4
JournalJournal of gastroenterology
Volume38
Issue numberSUPPL. 15
Publication statusPublished - Apr 28 2003

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Inflammation
Colitis
Cytokines
Therapeutics

All Science Journal Classification (ASJC) codes

  • Gastroenterology

Cite this

Strober, W., Fuss, I. J., Nakamura, K., & Kitani, A. (2003). Recent advances in the understanding of the induction and regulation of mucosal inflammation. Journal of gastroenterology, 38(SUPPL. 15), 55-58.

Recent advances in the understanding of the induction and regulation of mucosal inflammation. / Strober, Warren; Fuss, Ivan J.; Nakamura, Kazuhiko; Kitani, Atsushi.

In: Journal of gastroenterology, Vol. 38, No. SUPPL. 15, 28.04.2003, p. 55-58.

Research output: Contribution to journalReview article

Strober, W, Fuss, IJ, Nakamura, K & Kitani, A 2003, 'Recent advances in the understanding of the induction and regulation of mucosal inflammation', Journal of gastroenterology, vol. 38, no. SUPPL. 15, pp. 55-58.
Strober, Warren ; Fuss, Ivan J. ; Nakamura, Kazuhiko ; Kitani, Atsushi. / Recent advances in the understanding of the induction and regulation of mucosal inflammation. In: Journal of gastroenterology. 2003 ; Vol. 38, No. SUPPL. 15. pp. 55-58.
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