Recent Progress in the Synthesis of Deuterated Aldehyde

Tetsuro Shinada, Atsushi Nakayama, Hironori Okamura, Yoko Yasuno

Research output: Contribution to journalReview articlepeer-review

1 Citation (Scopus)

Abstract

Deuterium-labeled organic compounds have become indispensable research tools in scientific research. This review focuses on the synthesis of deuterated aldehydes (RCDO) in which the hydrogen at the formyl group is replaced with deuterium. Aldehydes are useful starting materials for organic synthesis. A variety of transformations and derivatizations involving carbon-carbon bond-forming reactions and heteroatom manipulations are possible at the formyl group. Consequently, RCDOs are expected to be a powerful starting material for the synthesis of deuterium-labeled compounds. Many efforts have been devoted to the synthesis of RCDO. The classical and advanced methods are described in this review.

Original languageEnglish
Pages (from-to)1461-1473
Number of pages13
JournalBulletin of the Chemical Society of Japan
Volume95
Issue number10
DOIs
Publication statusPublished - Oct 2022

All Science Journal Classification (ASJC) codes

  • Chemistry(all)

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