[Recent topics in neurophysiological studies of patients with schizophrenia].

Research output: Contribution to journalReview article

1 Citation (Scopus)

Abstract

It has been suggested that psychotic symptoms of schizophrenia are associated with brain dysfunction at least to some extent. This article overviewed hot topics in neurophysiological studies of patients with schizophrenia. Moreover, it focused on recent findings in electroencephalography and magnetoencephalography. First, the author introduced auditory mismatch negativities (MMN), auditory P300, face N170, and gamma band neural oscillations. Findings of MMN and P300 supported schizophrenia being characterized by brain dysfunctions, some of which occur before full symptom onset and some progress in the 1-2 years after onset. In addition, neurophysiological indices for social dysfunction may lead to new preventive approaches. Finally, neural oscillations are possible translational paradigms, since they can be recorded from animals, healthy subjects, and patients with schizophrenia. To understand the pathophysiology of schizophrenia, neurophysiological efforts are important.

Original languageEnglish
Pages (from-to)847-852
Number of pages6
JournalSeishin shinkeigaku zasshi = Psychiatria et neurologia Japonica
Volume115
Issue number8
Publication statusPublished - Jan 1 2013

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Schizophrenia
Magnetoencephalography
Brain
Electroencephalography
Healthy Volunteers

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

[Recent topics in neurophysiological studies of patients with schizophrenia]. / Onitsuka, Toshiaki.

In: Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica, Vol. 115, No. 8, 01.01.2013, p. 847-852.

Research output: Contribution to journalReview article

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