Recent trends of asymmetric catalysis with water as a nucleophile

Research output: Contribution to journalReview articlepeer-review

Abstract

Utilizing water as a reagent is one of the important topics in synthetic organic chemistry due to unique features of water for green chemistry. This review outlines recent trends of asymmetric catalysis with water as a nucleophile, and mainly picks up transition metal catalyzed asymmetric allylic substitution with a water nucleophile and enantioselective O-H insertion of α-aryldiazoesters with water. Former one contains a mechanistically rare example that the enantioselection occurs in the nucleophilic attack of metal hydroxide species to electrophiles.

Original languageEnglish
Pages (from-to)949-950
Number of pages2
JournalYuki Gosei Kagaku Kyokaishi/Journal of Synthetic Organic Chemistry
Volume70
Issue number9
DOIs
Publication statusPublished - 2012
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Organic Chemistry

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